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VT Cosmetics PDRN Cream 100 ingredients: is it worth it?
A competent barrier moisturizer wearing a PDRN marketing costume—not a transformative anti-aging treatment.
A competent barrier moisturizer wearing a PDRN marketing costume—not a transformative anti-aging treatment.
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The efficacy score of 4.4/5 comes from substantial humectant support, mid-list niacinamide, panthenol, fatty emollients, and a notably complete ceramide–cholesterol–phytosphingosine system, although the barrier lipids and most hyaluronic-acid forms appear late and are likely lower-concentration supporting ingredients. Sodium DNA is the headline marketing story, but it does not meaningfully drive the score because topical evidence is limited; the formula's real benefit is moisturization and barrier support. The safety score of 4.3/5 reflects a fragrance-free formula with no denatured alcohol or aggressive surfactants, offset by a rich base containing ethylhexyl palmitate and multiple botanical extracts that may not suit acne-prone or highly reactive skin. Ulta lists the 1.69-ounce product at $26.00.
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DemythSkin rates VT Cosmetics PDRN Cream 100 4.4/5 for efficacy and 4.3/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFORMULATION BASE (22)⌄
FULL INGREDIENT LIST⌄
Water, Glycerin, Butylene Glycol, Propanediol, C12-15 Alkyl Benzoate, Methyl Hydrogenated Rosinate, Polyglycerin-3, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Caprylic/Capric/Myristic/Stearic Triglyceride, Niacinamide, C14-22 Alcohols, Bis-Diglyceryl Polyacyladipate-2, Vinyl Dimethicone, Cetearyl Alcohol, Palmitic Acid, Betaine, Glyceryl Stearate, Panthenol, Polyacrylate-13, Stearic Acid, C12-20 Alkyl Glucoside, Hydrogenated Vegetable Oil, Cetearyl Glucoside, Hydrogenated Polyisobutene, Macadamia Ternifolia Seed Oil, Glyceryl Acrylate/Acrylic Acid Copolymer, Carbomer, Tromethamine, Xanthan gum, Ethylhexylglycerin, Allantoin, Adenosine, Ethylhexyl Palmitate, Polyglyceryl-10 Laurate, Sorbitan Isostearate, Disodium EDTA, Cyamopsis Tetragonoloba (Guar) Gum, Agar, Hydrogenated Lecithin, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Glucose, Coccinia Indica Fruit Extract, Sodium Hyaluronate, Panax Ginseng Root Extract, Solanum Melongena (Eggplant) Fruit Extract, Eclipta Prostrata Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Simmondsia Chinensis (Jojoba) Seed Oil, Curcuma Longa (Turmeric) Root Extract, Amber Powder, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Moringa Oleifera Seed Oil, Ceramide NP , Pentylene Glycol, Sodium DNA, Sodium Hyaluronate Crosspolymer, Ceramide NS , Cholesterol, Phytosphingosine, Sodium Acetylated Hyaluronate, Sodium Guaiazulene Sulfonate, Ceramide AP, Ceramide AS , Ceramide EOP.
WHAT EACH INGREDIENT DOES (24)⌄
- Water
- Solvent
- Glycerin
- Humectant
- Butylene Glycol
- Humectant and solvent
- Propanediol
- Humectant and solvent
- C12-15 Alkyl Benzoate
- Light emollient
- Methyl Hydrogenated Rosinate
- Emollient
- Polyglycerin-3
- Humectant
- Caprylic/Capric Triglyceride
- Emollient
- 1,2-Hexanediol
- Solvent and preservative booster
- Caprylic/Capric/Myristic/Stearic Triglyceride
- Emollient
- Niacinamide
- Barrier and tone support
- C14-22 Alcohols
- Emulsion stabilizer
- Bis-Diglyceryl Polyacyladipate-2
- Emollient
- Vinyl Dimethicone
- Skin-conditioning silicone
- Cetearyl Alcohol
- Fatty alcohol emulsifier
- Palmitic Acid
- Fatty-acid emollient
- Betaine
- Humectant and conditioner
- Glyceryl Stearate
- Emollient emulsifier
- Panthenol
- Humectant and soothing agent
- Polyacrylate-13
- Thickener and stabilizer
- Stearic Acid
- Fatty-acid emollient
- C12-20 Alkyl Glucoside
- Emulsifier
- Hydrogenated Vegetable Oil
- Occlusive emollient
- Cetearyl Glucoside
- Emulsifier
EXTERNAL CITATIONS
Ceramides and cholesterol: Barrier-lipid replacement supports skin-barrier function
Niacinamide: Well-studied barrier-support and tone-modulating ingredient
Hyaluronic acid derivatives: Humectant hydration support
Panthenol: Humectant and soothing support
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
A cheaper moisturizer with a close formula
51% formula match, by ingredient list. Labels don't state amounts, so strengths may differ.
VT Cosmetics PDRN Cream 100: common questions
Is VT Cosmetics PDRN Cream 100 worth it?
VT Cosmetics PDRN Cream 100 scores 4.4 out of 5.0 for efficacy (Effective) and 4.3 out of 5.0 for safety (Gentle) on DemythSkin's independent ingredient analysis. A competent barrier moisturizer wearing a PDRN marketing costume—not a transformative anti-aging treatment.
What are the key active ingredients in VT Cosmetics PDRN Cream 100?
VT Cosmetics PDRN Cream 100 contains no gold-standard actives. Its formula is built on supporting and base ingredients rather than clinically transformative actives.
Does VT Cosmetics PDRN Cream 100 contain fragrance or known irritants?
DemythSkin flags these ingredients in VT Cosmetics PDRN Cream 100 as documented irritants: Methyl Hydrogenated Rosinate, Hydrogenated Vegetable Oil, Moringa Oleifera Seed Oil.
How is VT Cosmetics PDRN Cream 100 scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
Free scores for every product in the database, or see them on Sephora, Ulta and Amazon with the Chrome extension.