TIRTIR Azelaic Acid 12% Serum — Efficacy 4.5/5.0, Safety 4.6/5.0 | DemythSkin
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[ DemythSkin Verdict ]
TIRTIR Azelaic Acid 12% Serum
Tirtir

TIRTIR Azelaic Acid 12% Serum

SerumAcne / Oil Control
Efficacy
Exceptional
4.5 / 5.0
Safety
Safe
4.6 / 5.0
System Verdict
Solid high-concentration azelaic acid serum that effectively targets acne and redness with supportive soothing actives. Efficacy score of 4.5 reflects 12% azelaic acid in position 2 (likely >10% concentration, optimal for anti-acne/rosacea), paired with Zinc PCA for sebum control and anti-microbial synergy, Panthenol/Ceramide NP for barrier support, plus humectants; no pH issues noted for dicarboxylic acid stability, Tocopherol adds antioxidant protection without jar packaging concerns.
Active Ingredients Detected
S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative
Azelaic Acid
A Tier: Good BasicsProven Results
PanthenolSorbitolTocopherolBetaineHyaluronic Acid/Polyisopropylacrylamide CopolymerCeramide NP
B Tier: Supporting IngredientsPromising Ingredients
GlucoseFructooligosaccharidesFructoseBiosaccharide Gum-1Zinc PCACaprylyl/Capryl Glucoside
C Tier: Marketing IdolsHype | Limited or Weak Data
Chondrus Crispus ExtractChlorella Vulgaris ExtractSaccharum Officinarum Extract
What Each Ingredient Does
Water
Solvent
Azelaic Acid
Anti-acne exfoliant
Propylene Glycol
Humectant solvent
Sodium Hydroxide
pH adjuster
Pentylene Glycol
Humectant preservative
Panthenol
Soothing humectant
Sorbitol
Humectant thickener
Chondrus Crispus Extract
Moisturizing film-former
Hydroxyethylcellulose
Thickener stabilizer
Chlorella Vulgaris Extract
Skin conditioning
Glucose
Humectant
Saccharum Officinarum Extract
Moisturizing exfoliant
1,2-Hexanediol
Humectant preservative
Butylene Glycol
Humectant solvent
Fructooligosaccharides
Humectant
Fructose
Humectant
Ethylhexylglycerin
Preservative booster
Biosaccharide Gum-1
Humectant soother
Tromethamine
pH adjuster
Xanthan Gum
Thickener stabilizer
Tocopherol
Antioxidant
Betaine
Humectant protector
Zinc PCA
Sebum regulator
Dipropylene Glycol
Humectant solvent
Full Ingredient List (INCI)

Water, Azelaic Acid, Propylene Glycol, Sodium Hydroxide, Pentylene Glycol, Panthenol, Sorbitol, Chondrus Crispus Extract, Hydroxyethylcellulose, Chlorella Vulgaris Extract, Glucose, Saccharum Officinarum Extract, 1,2-Hexanediol, Butylene Glycol, Fructooligosaccharides, Fructose, Ethylhexylglycerin, Biosaccharide Gum-1, Tromethamine, Xanthan Gum, Tocopherol, Betaine, Zinc PCA, Dipropylene Glycol, Hyaluronic Acid/Polyisopropylacrylamide Copolymer, Caprylyl/Capryl Glucoside, Hydrogenated Lecithin, Ceramide NP

Frequently Asked

Is TIRTIR Azelaic Acid 12% Serum worth it?

TIRTIR Azelaic Acid 12% Serum scores 4.5 out of 5.0 for efficacy (Exceptional) and 4.6 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. Solid high-concentration azelaic acid serum that effectively targets acne and redness with supportive soothing actives. Efficacy score of 4.5 reflects 12% azelaic acid in position 2 (likely >10% concentration, optimal fo

What are the key active ingredients in TIRTIR Azelaic Acid 12% Serum?

TIRTIR Azelaic Acid 12% Serum contains these gold-standard actives with strong clinical evidence: Azelaic Acid.

Does TIRTIR Azelaic Acid 12% Serum contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in TIRTIR Azelaic Acid 12% Serum. It scores 4.6 out of 5.0 for safety.

How is TIRTIR Azelaic Acid 12% Serum scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

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Analysis last updated: 2026-05-05. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score. DemythSkin earns commission from affiliate links (Amazon Associates and others). Scores are computed before any commercial relationship — the link follows the verdict, never the other way around.