SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule — Efficacy 4.1/5.0, Safety 4.3/5.0 | DemythSkin
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[ DemythSkin Verdict ]
SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule
SKIN1004

SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule

SerumBrightening
Efficacy
Strong
4.1 / 5.0
Safety
Safe
4.3 / 5.0
System Verdict
Legit brightening serum, but the headline 10% niacinamide does most of the work. The efficacy score is driven by a strong, evidence-backed trio of niacinamide, tranexamic acid, and ascorbyl glucoside, with panthenol, centella, and madecassoside adding meaningful soothing support; the spicule system may help delivery, but it is not the main reason this formula should work. It is not a perfectly optimized treatment because the formula does not disclose pH or any proof that every brightening active is at ideal strength, and the Sodium DNA element is marketing framing rather than a core efficacy driver.
Active Ingredients Detected
S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative
Tranexamic Acid
A Tier: Good BasicsProven Results
NiacinamideAscorbyl GlucosidePolyglutamic AcidTocopheryl AcetatePanthenolMadecassoside
B Tier: Supporting IngredientsPromising Ingredients
Centella Asiatica Extract
C Tier: Marketing IdolsHype | Limited or Weak Data
Hydrolyzed SpongeSodium DNA
What Each Ingredient Does
Water
solvent base
Butylene Glycol
humectant solvent
Niacinamide
brightening barrier support
1,2-Hexanediol
preservative booster
Ascorbyl Glucoside
vitamin C derivative
Propanediol
solvent humectant
Carbomer
gelling agent
Methylpropanediol
solvent penetration aid
Tromethamine
pH adjuster
Xanthan Gum
thickener stabilizer
Tranexamic Acid
brightening active
Centella Asiatica Extract
soothing botanical
Polyglutamic Acid
humectant film former
Hydrolyzed Sponge
spicule delivery system
Disodium EDTA
chelator stabilizer
Citric Acid
pH adjuster
Sodium DNA
marketing active
Ethylhexylglycerin
preservative booster
Tocopheryl Acetate
antioxidant emollient
Panthenol
soothing humectant
Madecassoside
calming active
Full Ingredient List (INCI)

Water, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Ascorbyl Glucoside, Propanediol, Carbomer, Methylpropanediol, Tromethamine, Xanthan Gum, Tranexamic Acid, Centella Asiatica Extract, Polyglutamic Acid, Hydrolyzed Sponge, Disodium EDTA, Citric Acid, Sodium DNA, Ethylhexylglycerin, Tocopheryl Acetate, Panthenol, Madecassoside

Frequently Asked

Is SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule worth it?

SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule scores 4.1 out of 5.0 for efficacy (Strong) and 4.3 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. Legit brightening serum, but the headline 10% niacinamide does most of the work. The efficacy score is driven by a strong, evidence-backed trio of niacinamide, tranexamic acid, and ascorbyl glucoside, with panthenol, cen

What are the key active ingredients in SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule?

SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule contains these gold-standard actives with strong clinical evidence: Tranexamic Acid.

Does SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule. It scores 4.3 out of 5.0 for safety.

How is SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

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Analysis last updated: 2026-07-29. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score. DemythSkin earns commission from affiliate links (Amazon Associates and others). Scores are computed before any commercial relationship — the link follows the verdict, never the other way around.