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SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule ingredients: is it worth it?
Solid pore-refining serum with clinical-level 10% niacinamide boosted by spicules, but efficacy held back by weak Vitamin C derivative and suboptimal antioxidant synergy.

Solid pore-refining serum with clinical-level 10% niacinamide boosted by spicules, but efficacy held back by weak Vitamin C derivative and suboptimal antioxidant synergy.
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Efficacy score of 4.4 reflects high 10% niacinamide (optimal for pores/brightening at this concentration, stable in water-based formula), effective spicule delivery system (13μm size < pore size for penetration per brand study), and supportive tranexamic acid + centella; deductions for Ascorbyl Glucoside (less potent than L-ascorbic acid, ~10-20% conversion efficiency) and Tocopheryl Acetate (weaker, esterified Vitamin E lacking ferulic synergy), no pH issues evident but citric acid/tromethamine suggest neutral pH fine for niacinamide.
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DemythSkin rates SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule 4.5/5 for efficacy and 4.9/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFULL INGREDIENT LIST⌄
Water, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Ascorbyl Glucoside, Propanediol, Carbomer, Methylpropanediol, Tromethamine, Xanthan Gum, Tranexamic Acid, Centella Asiatica Extract, Polyglutamic Acid, Hydrolyzed Sponge, Disodium EDTA, Citric Acid, Sodium DNA, Ethylhexylglycerin, Tocopheryl Acetate, Panthenol, Madecassoside
WHAT EACH INGREDIENT DOES (9)⌄
- Niacinamide
- Pore refining, brightening
- Ascorbyl Glucoside
- Stabilized Vitamin C
- Tranexamic Acid
- Skin brightening, soothing
- Centella Asiatica Extract
- Soothing, antioxidant
- Panthenol
- Moisturizing, soothing
- Madecassoside
- Antioxidant, soothing
- Polyglutamic Acid
- Intense humectant
- Hydrolyzed Sponge
- Micro-spicules for delivery
- Tocopheryl Acetate
- Vitamin E derivative
EXTERNAL CITATIONS
Niacinamide: Proven at 4-5%+ for anti-aging, pores, barrier (INCI Decoder)
Hydrolyzed Sponge: Absorption test, Korea Dermatology Research Institute 2025
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
A cheaper serum that scores as high or higher
A different formula for the same concern (brightening) that scores at least as high on both efficacy and safety.

SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule: common questions
Is SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule worth it?
SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule scores 4.5 out of 5.0 for efficacy (Gold Standard) and 4.9 out of 5.0 for safety (Very Gentle) on DemythSkin's independent ingredient analysis. Solid pore-refining serum with clinical-level 10% niacinamide boosted by spicules, but efficacy held back by weak Vitamin C derivative and suboptimal antioxidant synergy.
What are the key active ingredients in SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule?
SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule contains these gold-standard actives with strong clinical evidence: Tranexamic Acid.
Does SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule contain fragrance or known irritants?
DemythSkin's analysis found no flagged irritants in SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule. It scores 4.9 out of 5.0 for safety.
How is SKIN1004 Madagascar Centella Niacinamide 10 Boosting Shot Ampoule scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
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