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SKIN1004 Azelaic Acid 10% Ampoule ingredients: is it worth it?
This is a high-efficacy azelaic acid treatment ampoule with a genuinely strong 3X azelaic complex and a well-built soothing, hydrating base.
This is a high-efficacy azelaic acid treatment ampoule with a genuinely strong 3X azelaic complex and a well-built soothing, hydrating base.
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The formula delivers a full 10% azelaic acid plus two azelaic derivatives at quantified levels (1% potassium azeloyl diglycinate, 0.5% azelamide MEA) that together provide robust evidence-backed benefits for acne, redness, post-acne marks, and texture, while centella, panthenol, beta-glucan, hyaluronic acid and licorice root create a supportive environment that lets you use this relatively potent acid with far less irritation than a bare-bones azelaic formula. The azelaic system concentration and positioning, plus leave-on format, justify a high treatment efficacy score; there are no obvious pH or packaging constraints here, and the rest of the base is focused on humectancy and barrier comfort rather than dilute ‘decorative’ actives.
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DemythSkin rates SKIN1004 Azelaic Acid 10% Ampoule 4.5/5 for efficacy and 4.6/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFORMULATION BASE (8)⌄
FULL INGREDIENT LIST⌄
Water, Azelaic Acid, Hydroxypropyl Cyclodextrin, Disodium Phosphate, Pentylene Glycol, Propanediol, Potassium Azeloyl Diglycinate, Maltodextrin, Azelamide MEA, Panthenol, Butylene Glycol, 1,2-Hexanediol, Glycerin, Ethylhexylglycerin, Allantoin, Centella Asiatica Extract, Melia Azadirachta Leaf Extract, Biosaccharide Gum-1, Sodium Hyaluronate, Melia Azadirachta Flower Extract, Beta-Glucan, Centella Asiatica Leaf Extract, Phellinus Linteus Extract, Tocopherol, Citric Acid, Sodium Citrate, Glycyrrhiza Glabra (Licorice) Root Extract
WHAT EACH INGREDIENT DOES (24)⌄
- Water
- Solvent, formula base
- Azelaic Acid
- Multifunctional anti-acne active
- Hydroxypropyl Cyclodextrin
- Solubilizer, delivery aid
- Disodium Phosphate
- pH buffer, stabilizer
- Pentylene Glycol
- Humectant and solvent
- Propanediol
- Solvent, penetration enhancer
- Potassium Azeloyl Diglycinate
- Azelaic derivative, brightening
- Maltodextrin
- Stabilizer, texture aid
- Azelamide MEA
- Azelaic derivative for texture care
- Panthenol
- Humectant, barrier support
- Butylene Glycol
- Humectant and solvent
- 1,2-Hexanediol
- Solvent, preservative booster
- Glycerin
- Core humectant for hydration
- Ethylhexylglycerin
- Preservative booster, humectant
- Allantoin
- Skin soothing and conditioning
- Centella Asiatica Extract
- Soothing, barrier support extract
- Melia Azadirachta Leaf Extract
- Botanical antioxidant, soothing
- Biosaccharide Gum-1
- Hydrating polysaccharide, skin feel
- Sodium Hyaluronate
- Hyaluronic acid humectant
- Melia Azadirachta Flower Extract
- Botanical antioxidant extract
- Beta-Glucan
- Soothing and hydrating polysaccharide
- Centella Asiatica Leaf Extract
- Soothing centella fraction
- Phellinus Linteus Extract
- Fungal extract, antioxidant
- Tocopherol
- Vitamin E antioxidant
EXTERNAL CITATIONS
Azelaic Acid: Multiple clinical studies show 15–20% azelaic acid improves inflammatory acne, post-inflammatory hyperpigmentation, and rosacea-like redness; lower-strength 10% leave-on formulas still demonstrate comedolytic, anti-inflammatory and antimicrobial activity suitable for mild to moderate acne and dyschromia.
Potassium Azeloyl Diglycinate: Brand and third-party technical literature describe potassium azeloyl diglycinate as an azelaic-derived brightener that reduces sebum and improves hydration with good tolerability, supporting its use around 1% for oil-balance and tone-evening benefits.
Panthenol: Topical panthenol has documented barrier-repair and anti-irritant effects, reducing TEWL and improving stratum corneum hydration in controlled studies.
Centella Asiatica Extract: Centella asiatica triterpenes have shown wound-healing, anti-inflammatory, and barrier-supportive effects in in vitro and clinical data, making them useful for calming irritation and supporting compromised skin.
Beta-Glucan: Beta-glucan is a polysaccharide humectant with reported soothing and barrier-support effects, reducing erythema and improving hydration in cosmetic studies.
Glycyrrhiza Glabra (Licorice) Root Extract: Licorice root constituents (e.g., glabridin) have demonstrated tyrosinase-inhibiting and anti-inflammatory activity, supporting use for brightening and calming post-inflammatory pigmentation and redness.
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
A cheaper serum with a similar formula
A partial ingredient match (31%), not a close dupe.
SKIN1004 Azelaic Acid 10% Ampoule: common questions
Is SKIN1004 Azelaic Acid 10% Ampoule worth it?
SKIN1004 Azelaic Acid 10% Ampoule scores 4.5 out of 5.0 for efficacy (Gold Standard) and 4.6 out of 5.0 for safety (Very Gentle) on DemythSkin's independent ingredient analysis. This is a high-efficacy azelaic acid treatment ampoule with a genuinely strong 3X azelaic complex and a well-built soothing, hydrating base.
What are the key active ingredients in SKIN1004 Azelaic Acid 10% Ampoule?
SKIN1004 Azelaic Acid 10% Ampoule contains these gold-standard actives with strong clinical evidence: Azelaic Acid.
Does SKIN1004 Azelaic Acid 10% Ampoule contain fragrance or known irritants?
DemythSkin's analysis found no flagged irritants in SKIN1004 Azelaic Acid 10% Ampoule. It scores 4.6 out of 5.0 for safety.
How is SKIN1004 Azelaic Acid 10% Ampoule scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
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