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[ DemythSkin Verdict ]

SKIN1004

SKIN1004 Azelaic Acid 10% Ampoule

Name: SKIN1004 Azelaic Acid 10% Ampoule
Brand: SKIN1004

SerumAcne / Oil Control

Efficacy

Exceptional

4.5 / 5.0

Safety

Safe

4.6 / 5.0

System Verdict

This is a high-efficacy azelaic acid treatment ampoule with a genuinely strong 3X azelaic complex and a well-built soothing, hydrating base. The formula delivers a full 10% azelaic acid plus two azelaic derivatives at quantified levels (1% potassium azeloyl diglycinate, 0.5% azelamide MEA) that together provide robust evidence-backed benefits for acne, redness, post-acne marks, and texture, while centella, panthenol, beta-glucan, hyaluronic acid and licorice root create a supportive environment that lets you use this relatively potent acid with far less irritation than a bare-bones azelaic formula. The azelaic system concentration and positioning, plus leave-on format, justify a high treatment efficacy score; there are no obvious pH or packaging constraints here, and the rest of the base is focused on humectancy and barrier comfort rather than dilute ‘decorative’ actives.

Active Ingredients Detected

S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative

Azelaic Acid

A Tier: Good BasicsProven Results

Potassium Azeloyl DiglycinatePanthenolGlycerinAllantoinSodium HyaluronateBeta-GlucanTocopherol

B Tier: Supporting IngredientsPromising Ingredients

Hydroxypropyl CyclodextrinDisodium PhosphateMaltodextrinAzelamide MEACentella Asiatica ExtractBiosaccharide Gum-1Centella Asiatica Leaf Extract

C Tier: Marketing IdolsHype | Limited or Weak Data

Melia Azadirachta Leaf ExtractMelia Azadirachta Flower ExtractPhellinus Linteus ExtractGlycyrrhiza Glabra (Licorice) Root Extract

What Each Ingredient Does

Water: Solvent, formula base
Azelaic Acid: Multifunctional anti-acne active
Hydroxypropyl Cyclodextrin: Solubilizer, delivery aid
Disodium Phosphate: pH buffer, stabilizer
Pentylene Glycol: Humectant and solvent
Propanediol: Solvent, penetration enhancer
Potassium Azeloyl Diglycinate: Azelaic derivative, brightening
Maltodextrin: Stabilizer, texture aid
Azelamide MEA: Azelaic derivative for texture care
Panthenol: Humectant, barrier support
Butylene Glycol: Humectant and solvent
1,2-Hexanediol: Solvent, preservative booster
Glycerin: Core humectant for hydration
Ethylhexylglycerin: Preservative booster, humectant
Allantoin: Skin soothing and conditioning
Centella Asiatica Extract: Soothing, barrier support extract
Melia Azadirachta Leaf Extract: Botanical antioxidant, soothing
Biosaccharide Gum-1: Hydrating polysaccharide, skin feel
Sodium Hyaluronate: Hyaluronic acid humectant
Melia Azadirachta Flower Extract: Botanical antioxidant extract
Beta-Glucan: Soothing and hydrating polysaccharide
Centella Asiatica Leaf Extract: Soothing centella fraction
Phellinus Linteus Extract: Fungal extract, antioxidant
Tocopherol: Vitamin E antioxidant

Full Ingredient List (INCI)

Water, Azelaic Acid, Hydroxypropyl Cyclodextrin, Disodium Phosphate, Pentylene Glycol, Propanediol, Potassium Azeloyl Diglycinate, Maltodextrin, Azelamide MEA, Panthenol, Butylene Glycol, 1,2-Hexanediol, Glycerin, Ethylhexylglycerin, Allantoin, Centella Asiatica Extract, Melia Azadirachta Leaf Extract, Biosaccharide Gum-1, Sodium Hyaluronate, Melia Azadirachta Flower Extract, Beta-Glucan, Centella Asiatica Leaf Extract, Phellinus Linteus Extract, Tocopherol, Citric Acid, Sodium Citrate, Glycyrrhiza Glabra (Licorice) Root Extract

Frequently Asked

Is SKIN1004 Azelaic Acid 10% Ampoule worth it?

SKIN1004 Azelaic Acid 10% Ampoule scores 4.5 out of 5.0 for efficacy (Exceptional) and 4.6 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. This is a high-efficacy azelaic acid treatment ampoule with a genuinely strong 3X azelaic complex and a well-built soothing, hydrating base. The formula delivers a full 10% azelaic acid plus two azelaic derivatives at qu

What are the key active ingredients in SKIN1004 Azelaic Acid 10% Ampoule?

SKIN1004 Azelaic Acid 10% Ampoule contains these gold-standard actives with strong clinical evidence: Azelaic Acid.

Does SKIN1004 Azelaic Acid 10% Ampoule contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in SKIN1004 Azelaic Acid 10% Ampoule. It scores 4.6 out of 5.0 for safety.

How is SKIN1004 Azelaic Acid 10% Ampoule scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

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Analysis last updated: 2026-07-29. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score. DemythSkin earns commission from affiliate links (Amazon Associates and others). Scores are computed before any commercial relationship — the link follows the verdict, never the other way around.