PURITO Retinol Retinal 2000 NAD+ Serum — Efficacy 4.5/5.0, Safety 4.1/5.0 | DemythSkin
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[ DemythSkin Verdict ]
PURITO Retinol Retinal 2000 NAD+ Serum
PURITO

PURITO Retinol Retinal 2000 NAD+ Serum

SerumAnti-Aging
Efficacy
Exceptional
4.5 / 5.0
Safety
Mostly Safe
4.1 / 5.0
System Verdict
A legitimately strong retinoid serum, but the formula is still more “good anti-aging support” than a perfect clinical retinoid powerhouse. The efficacy score is driven mainly by the presence of two proven retinoids, retinol and retinal, plus meaningful support from niacinamide, adenosine, ceramide NP, glycerin, and hydrogenated lecithin; it is held back from a higher score because the retinoids are not quantified on the INCI panel beyond the marketing ppm claim, and the NAD+ framing is more branding than a proven topical driver.
Active Ingredients Detected
S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative
RetinolRetinal
A Tier: Good BasicsProven Results
GlycerinPolyglycerin-3NiacinamideHelianthus Annuus (Sunflower) Seed OilAdenosineLactococcus Ferment LysateTocopherolCyanocobalaminCeramide NP
B Tier: Supporting IngredientsPromising Ingredients
Methyl Gluceth-20Glycereth-26Gellan GumAgarPolyquaternium-51Beta-CaroteneNicotinamide Adenine DinucleotideCentella Asiatica ExtractFructooligosaccharidesMaltodextrinSodium ChlorideLevulinic AcidSodium Levulinate
C Tier: Marketing IdolsHype | Limited or Weak Data
Ficus Carica (Fig) Fruit ExtractActinidia Arguta Fruit ExtractHydrolyzed Gardenia Florida ExtractSophora Japonica Flower Extract
D Tier: Potential IrritantsBe Cautious
Phenylpropanol
What Each Ingredient Does
Water
solvent base
Glycerin
humectant
Caprylic/Capric Triglyceride
emollient texture support
Polyglycerin-3
humectant and solvent
Butylene Glycol
solvent humectant
1,2-Hexanediol
solvent preservative booster
Niacinamide
brightening and barrier support
Methyl Gluceth-20
humectant and slip agent
Glycereth-26
humectant and solvent
Pentylene Glycol
humectant and solvent
Sodium Citrate
pH buffer
Ethylhexylglycerin
preservative booster
Retinol
retinoid anti-aging active
Retinal
retinoid anti-aging active
Gellan Gum
gel thickener
Agar
gel former
Xanthan Gum
thickener stabilizer
Helianthus Annuus (Sunflower) Seed Oil
emollient lipid support
Adenosine
anti-wrinkle support
Lactococcus Ferment Lysate
ferment skin support
Polyquaternium-51
moisture-binding film former
Citric Acid
pH adjuster
Beta-Carotene
antioxidant pigment
Nicotinamide Adenine Dinucleotide
marketing cofactor
Full Ingredient List (INCI)

Water, Glycerin, Caprylic/capric Triglyceride, Polyglycerin-3, Butylene Glycol, 1,2-hexanediol, Niacinamide, Methyl Gluceth-20, Glycereth-26, Pentylene Glycol, Sodium Citrate, Ethylhexylglycerin, Retinol, Retinal, Gellan Gum, Agar, Xanthan Gum, Helianthus Annuus (Sunflower) Seed Oil, Adenosine, Lactococcus Ferment Lysate, Polyquaternium-51, Citric Acid, Beta-carotene, Nicotinamide Adenine Dinucleotide, Hydrogenated Lecithin, Tocopherol, Centella Asiatica Extract, Ficus Carica (Fig) Fruit Extract, Fructooligosaccharides, Cyanocobalamin, Ceramide Np, Maltodextrin, Arginine, Actinidia Arguta Fruit Extract, Hydrolyzed Gardenia Florida Extract, Sophora Japonica Flower Extract, Sodium Chloride, Phenylpropanol, Levulinic Acid, Sodium Levulinate

Frequently Asked

Is PURITO Retinol Retinal 2000 NAD+ Serum worth it?

PURITO Retinol Retinal 2000 NAD+ Serum scores 4.5 out of 5.0 for efficacy (Exceptional) and 4.1 out of 5.0 for safety (Mostly Safe) on DemythSkin's independent ingredient analysis. A legitimately strong retinoid serum, but the formula is still more “good anti-aging support” than a perfect clinical retinoid powerhouse. The efficacy score is driven mainly by the presence of two proven retinoids, reti

What are the key active ingredients in PURITO Retinol Retinal 2000 NAD+ Serum?

PURITO Retinol Retinal 2000 NAD+ Serum contains these gold-standard actives with strong clinical evidence: Retinol, Retinal.

Does PURITO Retinol Retinal 2000 NAD+ Serum contain fragrance or known irritants?

DemythSkin flags these ingredients in PURITO Retinol Retinal 2000 NAD+ Serum as potential irritants: Phenylpropanol.

How is PURITO Retinol Retinal 2000 NAD+ Serum scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

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Analysis last updated: 2026-08-17. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score. DemythSkin earns commission from affiliate links (Amazon Associates and others). Scores are computed before any commercial relationship — the link follows the verdict, never the other way around.