All scans / Serums / Prequel Multi-Quench Polyglutamic Acid Serum

[ DEMYTHSKIN_SCORE · SERUM ]

Prequel Multi-Quench Polyglutamic Acid Serum ingredients: is it worth it?

This is a straightforward hydration workhorse serum with no true treatment actives beyond humectants and one nice stress-protection molecule.

[ SCAN_RESULT ]
Prequel Multi-Quench Polyglutamic Acid Serum
— Prequel
Multi-Quench Polyglutamic Acid Serum
Hydration
Does it work?
3.6/ 5.0
Modest
Is it safe?
4.7/ 5.0
Very Gentle
THE VERDICT[=] Fair Price$28

This is a straightforward hydration workhorse serum with no true treatment actives beyond humectants and one nice stress-protection molecule.

READ MORE

The efficacy score is driven by a dense mix of well-established humectants (glycerin, butylene glycol, erythritol, polyglutamic acid) and an evidence-backed compatible solute (ectoin), at a skin-friendly pH around 5.5 that supports barrier comfort but offers no exfoliation, brightening, or anti-aging treatment effect; antioxidants and botanicals are present mainly as supporting players rather than high-impact actives.

Find on Amazon ↗→ Alternatives & dupes

We may earn a commission from qualifying purchases. Links never influence scores.

DemythSkin rates Prequel Multi-Quench Polyglutamic Acid Serum 3.6/5 for efficacy and 4.7/5 for safety.

GRADED AS SERUM — HYDRATION

ACTIVE INGREDIENTS BY TIER

◄ DRIVES RESULTSWORKS AGAINST YOU ►
Doing the work · 5 ingredients
S

Gold Standards

High clinical proof | Skin-transformative
None detected
A

Reliable

Proven results
GlycerinPolyglutamic AcidEctoinErythritolTocopherol
B

Potent

Developing evidence
None detected
Not doing the work · 1 ingredient
C

Overhyped | Marketing

Hype | Limited data
Hibiscus Sabdariffa Fruit Extract
D

Documented Irritants

Evidence-backed flag
None detected
FORMULATION BASE (12)⌄
Water (Aqua)Butylene Glycol1,2-HexanediolPhenoxyethanolPropanediolXanthan GumCaprylyl GlycolCarbomerEthylhexylglycerinAcrylates/C10-30 Alkyl Acrylate CrosspolymerCitric AcidSodium Hydroxide
FULL INGREDIENT LIST⌄

Water (Aqua), Glycerin, Butylene Glycol, Polyglutamic Acid, 1,2-Hexanediol, Ectoin, Hibiscus Sabdariffa Fruit Extract, Erythritol, Phenoxyethanol, Propanediol, Xanthan Gum, Caprylyl Glycol, Carbomer, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopherol, Citric Acid, Sodium Hydroxide.

WHAT EACH INGREDIENT DOES (18)⌄
Water (Aqua)
Primary solvent
Glycerin
Humectant for hydration
Butylene Glycol
Humectant and penetration aid
Polyglutamic Acid
Film-forming humectant
1,2-Hexanediol
Solvent and preservative booster
Ectoin
Stress-protection soothing osmolyte
Hibiscus Sabdariffa Fruit Extract
Botanical antioxidant and humectant
Erythritol
Humectant and moisturizer
Phenoxyethanol
Preservative
Propanediol
Solvent and humectant
Xanthan Gum
Viscosity control and stabilizer
Caprylyl Glycol
Emollient and preservative booster
Carbomer
Gel thickener
Ethylhexylglycerin
Preservative booster and humectant
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Polymer thickener and stabilizer
Tocopherol
Antioxidant (vitamin E)
Citric Acid
pH adjuster and chelator
Sodium Hydroxide
pH adjuster

EXTERNAL CITATIONS

Ectoin: Studies show ectoin functions as a compatible solute that helps protect skin cells from environmental stress and improves barrier resilience when used topically.

Polyglutamic Acid: Experimental data indicate polyglutamic acid can act as a film-forming humectant that enhances skin hydration and supports moisturization when combined with other humectants.

Glycerin: Clinical evidence supports glycerin as a cornerstone humectant that increases stratum corneum hydration and improves skin barrier function in leave-on formulations.

DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.

[ 01 · SCORES_HIGHER_FOR_LESS ]

A cheaper serum that scores as high or higher

A different formula for the same concern (hydration) that scores at least as high on both efficacy and safety.

e.l.f. Holy Hydration! Triple Bounce Serum
e.l.f.
Holy Hydration! Triple Bounce Serum
4.3 4.8 efficacy · safety
$12
SAVE $16
See the score →
[ 02 · FAQ ]

Prequel Multi-Quench Polyglutamic Acid Serum: common questions

Is Prequel Multi-Quench Polyglutamic Acid Serum worth it?

Prequel Multi-Quench Polyglutamic Acid Serum scores 3.6 out of 5.0 for efficacy (Modest) and 4.7 out of 5.0 for safety (Very Gentle) on DemythSkin's independent ingredient analysis. This is a straightforward hydration workhorse serum with no true treatment actives beyond humectants and one nice stress-protection molecule.

What are the key active ingredients in Prequel Multi-Quench Polyglutamic Acid Serum?

Prequel Multi-Quench Polyglutamic Acid Serum contains no gold-standard actives. Its formula is built on supporting and base ingredients rather than clinically transformative actives.

Does Prequel Multi-Quench Polyglutamic Acid Serum contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in Prequel Multi-Quench Polyglutamic Acid Serum. It scores 4.7 out of 5.0 for safety.

How is Prequel Multi-Quench Polyglutamic Acid Serum scored?

DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.

[ SCAN_YOUR_SHELF ]
Check the next product before you buy it.

Free scores for every product in the database, or see them on Sephora, Ulta and Amazon with the Chrome extension.