Prequel Multi-Quench Polyglutamic Acid Serum — Efficacy 3.9/5.0, Safety 4.7/5.0 | DemythSkin
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[ DemythSkin Verdict ]
Prequel Multi-Quench Polyglutamic Acid Serum
Prequel

Prequel Multi-Quench Polyglutamic Acid Serum

SerumHydration
Efficacy
Solid
3.9 / 5.0
Safety
Safe
4.7 / 5.0
System Verdict
This is a straightforward hydration workhorse serum with no true treatment actives beyond humectants and one nice stress-protection molecule. The efficacy score is driven by a dense mix of well-established humectants (glycerin, butylene glycol, erythritol, polyglutamic acid) and an evidence-backed compatible solute (ectoin), at a skin-friendly pH around 5.5 that supports barrier comfort but offers no exfoliation, brightening, or anti-aging treatment effect; antioxidants and botanicals are present mainly as supporting players rather than high-impact actives.
Active Ingredients Detected
A Tier: Good BasicsProven Results
GlycerinPolyglutamic AcidEctoinErythritolTocopherol
C Tier: Marketing IdolsHype | Limited or Weak Data
Hibiscus Sabdariffa Fruit Extract
What Each Ingredient Does
Water (Aqua)
Primary solvent
Glycerin
Humectant for hydration
Butylene Glycol
Humectant and penetration aid
Polyglutamic Acid
Film-forming humectant
1,2-Hexanediol
Solvent and preservative booster
Ectoin
Stress-protection soothing osmolyte
Hibiscus Sabdariffa Fruit Extract
Botanical antioxidant and humectant
Erythritol
Humectant and moisturizer
Phenoxyethanol
Preservative
Propanediol
Solvent and humectant
Xanthan Gum
Viscosity control and stabilizer
Caprylyl Glycol
Emollient and preservative booster
Carbomer
Gel thickener
Ethylhexylglycerin
Preservative booster and humectant
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Polymer thickener and stabilizer
Tocopherol
Antioxidant (vitamin E)
Citric Acid
pH adjuster and chelator
Sodium Hydroxide
pH adjuster
Full Ingredient List (INCI)

Water (Aqua), Glycerin, Butylene Glycol, Polyglutamic Acid, 1,2-Hexanediol, Ectoin, Hibiscus Sabdariffa Fruit Extract, Erythritol, Phenoxyethanol, Propanediol, Xanthan Gum, Caprylyl Glycol, Carbomer, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopherol, Citric Acid, Sodium Hydroxide.

Frequently Asked

Is Prequel Multi-Quench Polyglutamic Acid Serum worth it?

Prequel Multi-Quench Polyglutamic Acid Serum scores 3.9 out of 5.0 for efficacy (Solid) and 4.7 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. This is a straightforward hydration workhorse serum with no true treatment actives beyond humectants and one nice stress-protection molecule. The efficacy score is driven by a dense mix of well-established humectants (gl

What are the key active ingredients in Prequel Multi-Quench Polyglutamic Acid Serum?

Prequel Multi-Quench Polyglutamic Acid Serum contains no gold-standard actives — its formula is built on supporting and base ingredients rather than clinically transformative actives.

Does Prequel Multi-Quench Polyglutamic Acid Serum contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in Prequel Multi-Quench Polyglutamic Acid Serum. It scores 4.7 out of 5.0 for safety.

How is Prequel Multi-Quench Polyglutamic Acid Serum scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

Analyze on DemythSkin →

Analysis last updated: 2026-08-24. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.