Peter Thomas Roth Retinol Fusion PM Night Serum — Efficacy 4.3/5.0, Safety 4.3/5.0 | DemythSkin
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[ DemythSkin Verdict ]
Peter Thomas Roth Retinol Fusion PM Night Serum
Peter Thomas Roth

Peter Thomas Roth Retinol Fusion PM Night Serum

SerumAnti-Aging
Efficacy
Strong
4.3 / 5.0
Safety
Safe
4.3 / 5.0
System Verdict
A legitimately effective retinol serum, but the alcohol and mostly supporting-base formula keep it from elite status. The efficacy score is driven by retinol being the clear headline active near the top of the list, plus a sensible supporting cast of squalane, bisabolol, and vitamin E/C antioxidant helpers; it loses points because the formula is relatively short, includes alcohol, and the antioxidant components are supportive rather than a robust treatment system.
Active Ingredients Detected
S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative
Retinol
A Tier: Good BasicsProven Results
SqualaneTocopheryl AcetateBisabolol
B Tier: Supporting IngredientsPromising Ingredients
Ascorbyl PalmitatePotassium PhosphateAlcohol
What Each Ingredient Does
Cyclopentasiloxane
volatile silicone slip agent
Squalane
emollient and barrier support
Water/Aqua/Eau
solvent
Retinol
primary anti-aging active
Tocopheryl Acetate
vitamin E antioxidant
Ascorbyl Palmitate
oil-soluble vitamin C derivative
Bisabolol
soothing skin-conditioning agent
Lecithin
emulsifier and skin conditioner
Potassium Phosphate
buffering agent
Pentylene Glycol
humectant and solvent
Polysorbate-20
solubilizer
Alcohol
solvent and texture modifier
Full Ingredient List (INCI)

Cyclopentasiloxane, Squalane, Water/Aqua/Eau, Retinol, Tocopheryl Acetate, Ascorbyl Palmitate, Bisabolol, Lecithin, Potassium Phosphate, Pentylene Glycol, Polysorbate-20, Alcohol.

Frequently Asked

Is Peter Thomas Roth Retinol Fusion PM Night Serum worth it?

Peter Thomas Roth Retinol Fusion PM Night Serum scores 4.3 out of 5.0 for efficacy (Strong) and 4.3 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. A legitimately effective retinol serum, but the alcohol and mostly supporting-base formula keep it from elite status. The efficacy score is driven by retinol being the clear headline active near the top of the list, plus

What are the key active ingredients in Peter Thomas Roth Retinol Fusion PM Night Serum?

Peter Thomas Roth Retinol Fusion PM Night Serum contains these gold-standard actives with strong clinical evidence: Retinol.

Does Peter Thomas Roth Retinol Fusion PM Night Serum contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in Peter Thomas Roth Retinol Fusion PM Night Serum. It scores 4.3 out of 5.0 for safety.

How is Peter Thomas Roth Retinol Fusion PM Night Serum scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

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Analysis last updated: 2026-10-05. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score. DemythSkin earns commission from affiliate links (Amazon Associates and others). Scores are computed before any commercial relationship — the link follows the verdict, never the other way around.