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[ DemythSkin Verdict ]

numbuzin

Numbuzin No.5+ Glutathione Vitamin Concentrated Serum

Name: Numbuzin No.5+ Glutathione Vitamin Concentrated Serum
Brand: numbuzin

SerumBrightening

Efficacy

Exceptional

4.6 / 5.0

Safety

Safe

4.4 / 5.0

System Verdict

This is a heavy-hitting brightening serum with a legitimately stacked formula, but its real-world impact hinges on consistent use and tolerance rather than miracle-level strength. The efficacy score is driven by a rare combination of multiple evidence-backed pigment regulators high in the list (niacinamide, tranexamic acid, alpha-arbutin) plus several vitamin C forms, supported by hydration and barrier-lipid ingredients that help the skin tolerate daily use; I’m holding it below the top echelon because the exact active percentages are undisclosed, the vitamin C derivatives are less proven than pure L-ascorbic in optimal conditions, and the brightening actives are numerous enough to raise irritation risk for some users rather than guaranteeing superior results.

Active Ingredients Detected

S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative

Tranexamic AcidAscorbic Acid

A Tier: Good BasicsProven Results

NiacinamidePanthenolSorbitolGlycerinButyrospermum Parkii (Shea) Butter3-O-Ethyl Ascorbic AcidAlpha-ArbutinBisabololBifida Ferment LysateAdenosineAllantoinSodium HyaluronateCeramide NPBeta-GlucanTocopherolAscorbyl GlucosideTocopheryl AcetateUbiquinone

B Tier: Supporting IngredientsPromising Ingredients

Neopentyl Glycol DicaprateDipotassium GlycyrrhizateHydroxypropyl CyclodextrinThioctic Acid

C Tier: Marketing IdolsHype | Limited or Weak Data

Vaccinium Vitis-Idaea Fruit ExtractChondrus Crispus ExtractSaccharum Officinarum (Sugarcane) ExtractGlutathioneMelia Azadirachta Flower ExtractOcimum Sanctum Leaf ExtractMelia Azadirachta Leaf ExtractCurcuma Longa (Turmeric) Root ExtractCorallina Officinalis ExtractTremella Fuciformis (Mushroom) Extract

What Each Ingredient Does

Water: solvent
Butylene Glycol: humectant solvent
Niacinamide: brightening and barrier support
Panthenol: soothing humectant
Tranexamic Acid: brightening pigment modulator
1,2-Hexanediol: solvent and preservative booster
Neopentyl Glycol Dicaprate: emollient texture enhancer
Caprylic/Capric Triglyceride: emollient and skin-conditioning
Sorbitol: humectant and viscosity modifier
Vaccinium Vitis-Idaea Fruit Extract: botanical antioxidant extract
Behenyl Alcohol: fatty alcohol thickener
Pentylene Glycol: humectant and solvent
Glycerin: primary humectant
Chondrus Crispus Extract: film-forming moisturizing extract
Butyrospermum Parkii (Shea) Butter: emollient and occlusive
3-O-Ethyl Ascorbic Acid: stable vitamin C derivative
Saccharum Officinarum (Sugarcane) Extract: botanical humectant extract
Carbomer: gel thickener and stabilizer
Alpha-Arbutin: brightening pigment inhibitor
Bisabolol: soothing anti-irritant
Tromethamine: pH adjuster
Ethylhexylglycerin: preservative booster and humectant
Bifida Ferment Lysate: probiotic lysate skin conditioner
Adenosine: skin-soothing and anti-wrinkle agent

Full Ingredient List (INCI)

Water, Butylene Glycol, Niacinamide, Panthenol, Tranexamic Acid, 1,2-Hexanediol, Neopentyl Glycol Dicaprate, Caprylic/Capric Triglyceride, Sorbitol, Vaccinium Vitis-Idaea Fruit Extract, Behenyl Alcohol, Pentylene Glycol, Glycerin, Chondrus Crispus Extract, Butyrospermum Parkii (Shea) Butter, 3-O-Ethyl Ascorbic Acid, Saccharum Officinarum (Sugarcane) Extract, Carbomer, Alpha-Arbutin, Bisabolol, Tromethamine, Ethylhexylglycerin, Bifida Ferment Lysate, Adenosine, Hydrogenated Lecithin, Allantoin, Sodium Hyaluronate, Xanthan Gum, Glutathione, Disodium EDTA, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Ceramide NP, Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Beta-Glucan, Dipotassium Glycyrrhizate, Tocopherol, Ascorbic Acid, Ascorbyl Glucoside, Tocopheryl Acetate, Hydroxypropyl Cyclodextrin, Ubiquinone, Thioctic Acid, Tremella Fuciformis (Mushroom) Extract, Potassium Hydroxide Double the Results Save More When You Bundle 25% OFF No.5 Spot-Fading Duo

Frequently Asked

Is Numbuzin No.5+ Glutathione Vitamin Concentrated Serum worth it?

Numbuzin No.5+ Glutathione Vitamin Concentrated Serum scores 4.6 out of 5.0 for efficacy (Exceptional) and 4.4 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. This is a heavy-hitting brightening serum with a legitimately stacked formula, but its real-world impact hinges on consistent use and tolerance rather than miracle-level strength. The efficacy score is driven by a rare c

What are the key active ingredients in Numbuzin No.5+ Glutathione Vitamin Concentrated Serum?

Numbuzin No.5+ Glutathione Vitamin Concentrated Serum contains these gold-standard actives with strong clinical evidence: Tranexamic Acid, Ascorbic Acid.

Does Numbuzin No.5+ Glutathione Vitamin Concentrated Serum contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in Numbuzin No.5+ Glutathione Vitamin Concentrated Serum. It scores 4.4 out of 5.0 for safety.

How is Numbuzin No.5+ Glutathione Vitamin Concentrated Serum scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

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Analysis last updated: 2026-08-25. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score. DemythSkin earns commission from affiliate links (Amazon Associates and others). Scores are computed before any commercial relationship — the link follows the verdict, never the other way around.