All scans / Serums / numbuzin No.5 Glutathione Vitamin Concentrated Serum
numbuzin No.5 Glutathione Vitamin Concentrated Serum ingredients: is it worth it?
This is a legitimately potent brightening and antioxidant serum, not just marketing fluff, but it’s moderately aggressive and not ideal for very sensitive skin.
This is a legitimately potent brightening and antioxidant serum, not just marketing fluff, but it’s moderately aggressive and not ideal for very sensitive skin.
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The efficacy is driven by high-position niacinamide (brand-disclosed ~5%), supported by tranexamic acid, multiple forms of vitamin C, lipo-hydroxy acid and gluconolactone for gentle exfoliation and pigment control, plus a robust humectant/soothing base (glycerin, hydroxyethyl urea, panthenol, betaine, sodium hyaluronate) and an antioxidant network (tocopherol, ubiquinone, hydroxyacetophenone) that can realistically help hyperpigmentation over weeks. I deduct some points for the inclusion of alcohol and the possibility of cumulative irritation when layering this with other strong actives, but overall the formula is well-constructed for brightening, with no reliance on hype-only ingredients like glutathione as the true workhorse.
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DemythSkin rates numbuzin No.5 Glutathione Vitamin Concentrated Serum 4.3/5 for efficacy and 4.1/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFORMULATION BASE (16)⌄
FULL INGREDIENT LIST⌄
Water, Niacinamide, Dipropylene Glycol, Glycerin, Propanediol, Butylene Glycol, Hydroxyethyl Urea, Diethoxyethyl Succinate, Hydroxyacetophenone, Caprylyl Glycol, Polyglyceryl-10 Laurate, Betaine, Citric Acid, Panthenol, Ethylhexylglycerin, Gluconolactone, Sodium Polyacrylate, Disodium EDTA, Ammonium Acryloyldimethyltaurate/VP Copolymer, Sodium Citrate, Maltodextrin, 1,2-Hexanediol, Gardenia Florida Fruit Extract, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ascorbic Acid, Pantolactone, Tocopherol, Capryloyl Salicylic Acid, Tranexamic Acid, Tremella Fuciformis (Mushroom) Extract, Caprylic/Capric Triglyceride, Ascorbyl Glucoside, Ubiquinone, Hydrogenated Lecithin, Magnesium Chloride, Alcohol, Glutathione, Polysorbate 80, Calcium Gluconate, Pyridoxine HCl, BHT, Yeast Extract, Cyanocobalamin.
WHAT EACH INGREDIENT DOES (24)⌄
- Water
- Solvent base
- Niacinamide
- Brightening and barrier support
- Dipropylene Glycol
- Solvent and texture enhancer
- Glycerin
- Humectant for hydration
- Propanediol
- Solvent and penetration enhancer
- Butylene Glycol
- Humectant and solvent
- Hydroxyethyl Urea
- Humectant, improves hydration
- Diethoxyethyl Succinate
- Emollient / texture enhancer
- Hydroxyacetophenone
- Antioxidant and preservative helper
- Caprylyl Glycol
- Humectant and preservative booster
- Polyglyceryl-10 Laurate
- Emulsifier / surfactant
- Betaine
- Osmolyte, soothing humectant
- Citric Acid
- pH adjuster
- Panthenol
- Soothing humectant, barrier support
- Ethylhexylglycerin
- Preservative booster and humectant
- Gluconolactone
- Polyhydroxy acid, mild exfoliant
- Sodium Polyacrylate
- Thickener and film former
- Disodium EDTA
- Chelating agent for stability
- Ammonium Acryloyldimethyltaurate/VP Copolymer
- Gel-forming thickener
- Sodium Citrate
- pH buffer and chelator
- Maltodextrin
- Stabilizer and humectant
- 1,2-Hexanediol
- Solvent and preservative helper
- Gardenia Florida Fruit Extract
- Botanical extract, antioxidant/colorant
- Dipotassium Glycyrrhizate
- Soothing anti-inflammatory agent
EXTERNAL CITATIONS
Niacinamide: Clinical trials show topical niacinamide at 4–5% improves hyperpigmentation, texture, fine lines, and barrier function over 8–12 weeks.
Tranexamic Acid: Multiple studies support topical tranexamic acid (2–5%) for melasma and dark spot reduction with relatively low irritation compared to classic hydroquinone.
Ascorbic Acid / Ascorbyl Glucoside: Vitamin C and its stable derivatives provide antioxidant protection and contribute to brightening and collagen support when used consistently.
Capryloyl Salicylic Acid: Lipo-hydroxy acid is a gentler salicylic-derived exfoliant that works at lower concentrations to refine texture and assist with pore and spot care.
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
numbuzin No.5 Glutathione Vitamin Concentrated Serum: common questions
Is numbuzin No.5 Glutathione Vitamin Concentrated Serum worth it?
numbuzin No.5 Glutathione Vitamin Concentrated Serum scores 4.3 out of 5.0 for efficacy (Effective) and 4.1 out of 5.0 for safety (Gentle) on DemythSkin's independent ingredient analysis. This is a legitimately potent brightening and antioxidant serum, not just marketing fluff, but it’s moderately aggressive and not ideal for very sensitive skin.
What are the key active ingredients in numbuzin No.5 Glutathione Vitamin Concentrated Serum?
numbuzin No.5 Glutathione Vitamin Concentrated Serum contains these gold-standard actives with strong clinical evidence: Ascorbic Acid, Tranexamic Acid.
Does numbuzin No.5 Glutathione Vitamin Concentrated Serum contain fragrance or known irritants?
DemythSkin's analysis found no flagged irritants in numbuzin No.5 Glutathione Vitamin Concentrated Serum. It scores 4.1 out of 5.0 for safety.
How is numbuzin No.5 Glutathione Vitamin Concentrated Serum scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
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