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[ DemythSkin Verdict ]

numbuzin

numbuzin No.5 Glutathione Vitamin Concentrated Serum

Name: numbuzin No.5 Glutathione Vitamin Concentrated Serum
Brand: numbuzin

SerumBrightening

Efficacy

Strong

4.3 / 5.0

Safety

Mostly Safe

4.1 / 5.0

System Verdict

This is a legitimately potent brightening and antioxidant serum, not just marketing fluff, but it’s moderately aggressive and not ideal for very sensitive skin. The efficacy is driven by high-position niacinamide (brand-disclosed ~5%), supported by tranexamic acid, multiple forms of vitamin C, lipo-hydroxy acid and gluconolactone for gentle exfoliation and pigment control, plus a robust humectant/soothing base (glycerin, hydroxyethyl urea, panthenol, betaine, sodium hyaluronate) and an antioxidant network (tocopherol, ubiquinone, hydroxyacetophenone) that can realistically help hyperpigmentation over weeks. I deduct some points for the inclusion of alcohol and the possibility of cumulative irritation when layering this with other strong actives, but overall the formula is well-constructed for brightening, with no reliance on hype-only ingredients like glutathione as the true workhorse.

Active Ingredients Detected

S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative

Ascorbic AcidTranexamic Acid

A Tier: Good BasicsProven Results

NiacinamideGlycerinHydroxyethyl UreaBetainePanthenolGluconolactoneSodium HyaluronateTocopherolCapryloyl Salicylic AcidAscorbyl GlucosideUbiquinonePyridoxine HClCyanocobalamin

B Tier: Supporting IngredientsPromising Ingredients

Diethoxyethyl SuccinateHydroxyacetophenoneMaltodextrinDipotassium GlycyrrhizatePantolactoneMagnesium ChlorideAlcoholCalcium GluconateBHT

C Tier: Marketing IdolsHype | Limited or Weak Data

Gardenia Florida Fruit ExtractTremella Fuciformis (Mushroom) ExtractGlutathioneYeast Extract

What Each Ingredient Does

Water: Solvent base
Niacinamide: Brightening and barrier support
Dipropylene Glycol: Solvent and texture enhancer
Glycerin: Humectant for hydration
Propanediol: Solvent and penetration enhancer
Butylene Glycol: Humectant and solvent
Hydroxyethyl Urea: Humectant, improves hydration
Diethoxyethyl Succinate: Emollient / texture enhancer
Hydroxyacetophenone: Antioxidant and preservative helper
Caprylyl Glycol: Humectant and preservative booster
Polyglyceryl-10 Laurate: Emulsifier / surfactant
Betaine: Osmolyte, soothing humectant
Citric Acid: pH adjuster
Panthenol: Soothing humectant, barrier support
Ethylhexylglycerin: Preservative booster and humectant
Gluconolactone: Polyhydroxy acid, mild exfoliant
Sodium Polyacrylate: Thickener and film former
Disodium EDTA: Chelating agent for stability
Ammonium Acryloyldimethyltaurate/VP Copolymer: Gel-forming thickener
Sodium Citrate: pH buffer and chelator
Maltodextrin: Stabilizer and humectant
1,2-Hexanediol: Solvent and preservative helper
Gardenia Florida Fruit Extract: Botanical extract, antioxidant/colorant
Dipotassium Glycyrrhizate: Soothing anti-inflammatory agent

Full Ingredient List (INCI)

Water, Niacinamide, Dipropylene Glycol, Glycerin, Propanediol, Butylene Glycol, Hydroxyethyl Urea, Diethoxyethyl Succinate, Hydroxyacetophenone, Caprylyl Glycol, Polyglyceryl-10 Laurate, Betaine, Citric Acid, Panthenol, Ethylhexylglycerin, Gluconolactone, Sodium Polyacrylate, Disodium EDTA, Ammonium Acryloyldimethyltaurate/VP Copolymer, Sodium Citrate, Maltodextrin, 1,2-Hexanediol, Gardenia Florida Fruit Extract, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ascorbic Acid, Pantolactone, Tocopherol, Capryloyl Salicylic Acid, Tranexamic Acid, Tremella Fuciformis (Mushroom) Extract, Caprylic/Capric Triglyceride, Ascorbyl Glucoside, Ubiquinone, Hydrogenated Lecithin, Magnesium Chloride, Alcohol, Glutathione, Polysorbate 80, Calcium Gluconate, Pyridoxine HCl, BHT, Yeast Extract, Cyanocobalamin.

Frequently Asked

Is numbuzin No.5 Glutathione Vitamin Concentrated Serum worth it?

numbuzin No.5 Glutathione Vitamin Concentrated Serum scores 4.3 out of 5.0 for efficacy (Strong) and 4.1 out of 5.0 for safety (Mostly Safe) on DemythSkin's independent ingredient analysis. This is a legitimately potent brightening and antioxidant serum, not just marketing fluff, but it’s moderately aggressive and not ideal for very sensitive skin. The efficacy is driven by high-position niacinamide (brand-

What are the key active ingredients in numbuzin No.5 Glutathione Vitamin Concentrated Serum?

numbuzin No.5 Glutathione Vitamin Concentrated Serum contains these gold-standard actives with strong clinical evidence: Ascorbic Acid, Tranexamic Acid.

Does numbuzin No.5 Glutathione Vitamin Concentrated Serum contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in numbuzin No.5 Glutathione Vitamin Concentrated Serum. It scores 4.1 out of 5.0 for safety.

How is numbuzin No.5 Glutathione Vitamin Concentrated Serum scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

Analyze on DemythSkin →

Analysis last updated: 2026-08-03. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.