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[ DemythSkin Verdict ]

numbuzin No.9 NAD+ Bio Lifting Essence
SerumAnti-Aging
Efficacy
Strong
4.4 / 5.0
Safety
Safe
4.3 / 5.0
System Verdict
This is an impressively over-engineered peptide bomb that likely delivers decent plumping and smoothing, but the ‘NAD+ + 50 peptides’ story is far more marketing flex than guaranteed S Tier performance. Efficacy is supported by a solid humectant/emollient base, mid-list niacinamide, adenosine, beta-glucan, cholesterol, multiple antioxidants, and a genuinely large peptide stack including Matrixyl-type, copper, and expression-line peptides, but most of the exotic peptides, growth factors, NAD+ and antioxidant jewelry sit low in the INCI where their real-world impact is limited and largely dependent on proprietary complexes rather than clearly evidence-based, high-concentration actives; that combination earns a strong A Tier anti-aging profile but not S Tier, clinically-optimized status.
Active Ingredients Detected
S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative
Ascorbic Acid Polypeptide
A Tier: Good BasicsProven Results
WaterGlycerinPolyglycerin-3DimethiconeNiacinamideButyrospermum Parkii (Shea) ButterSodium HyaluronateSaccharomyces/Copper FermentSaccharomyces/Iron FermentSaccharomyces/Magnesium FermentSaccharomyces/Silicon FermentSaccharomyces/Zinc FermentLeuconostoc/Radish Root Ferment FiltrateDimethicone CrosspolymerHydrogenated LecithinAdenosineCholesterolAdenosine TriphosphateBeta-GlucanTocopherolSodium LactatePanthenolTetradecyl Aminobutyroylvalylaminobutyric Urea TrifluoroacetatePalmitoyl Dipeptide-5 Diaminobutyroyl HydroxythreonineBiotinBiotinoyl Tripeptide-1Tocopheryl AcetateUbiquinone
B Tier: Supporting IngredientsPromising Ingredients
Hydrogenated Poly(C6-14 Olefin)Butylene GlycolPentaerythrityl TetraethylhexanoatePropanediol1,2-HexanediolMethylpropanediolHeptasodium Hexacarboxymethyl Dipeptide-12Glyceryl StearatePolyglyceryl-3 Methylglucose DistearateAmmonium Acryloyldimethyltaurate/VP CopolymerSodium PolyacrylatePentylene GlycolTromethaminePalmitic AcidStearic AcidSodium PhytateHydroxypropyl CyclodextrinNicotinamide Adenine DinucleotidePalmitoyl Tripeptide-5Copper GluconateCapryloyl Dipeptide-17Thioctic AcidPotassium HydroxideResveratrolHesperidin Methyl ChalconeSorbitan LaurateSteareth-20AstaxanthinHydroxyethylcelluloseAcetyl Dipeptide-1 Cetyl EsterDipeptide Diaminobutyroyl Benzylamide DiacetatePolysorbate 20Sodium CitrateDextranHexapeptide-2Magnesium ChlorideAcetyl Tetrapeptide-5Dipeptide-2Acetyl Hexapeptide-8Citric AcidPalmitoyl Tetrapeptide-7Acetyl Tetrapeptide-3Palmitoyl Tripeptide-8Dipeptide-4Hexapeptide-11Pentapeptide-18Tripeptide-3sh-Decapeptide-7sh-Octapeptide-4Palmitoyl Tripeptide-1Hexapeptide-9Oligopeptide-3Palmitoyl Hexapeptide-12Tripeptide-1Palmitoyl Pentapeptide-4Copper Tripeptide-1Caffeoyl Tripeptide-1Caffeoyl sh-Octapeptide-4Galloyl Pentapeptide-33Kojyl Carboxy Dipeptide-23Nicotinoyl Tripeptide-1Octapeptide-7Oligopeptide-1sh-Decapeptide-9sh-Oligopeptide-9sh-Pentapeptide-19AsparagineGlutamineTryptophanOligopeptide-2sh-Oligopeptide-2sh-Polypeptide-1sh-Polypeptide-22sh-Polypeptide-3Acetyl Octapeptide-3Acetyl Tetrapeptide-2Acetyl Tetrapeptide-9CarnosineNonapeptide-1Cetearyl AlcoholCarbomerXanthan GumChlorhexidine DigluconatePotassium Sorbate
C Tier: Marketing IdolsHype | Limited or Weak Data
Tremella Fuciformis (Mushroom) ExtractTrifolium Pratense (Clover) Flower ExtractGlutathionesh-Oligopeptide-1
D Tier: Potential IrritantsBe Cautious
Hydrogenated Vegetable OilHaematococcus Pluvialis OilEthylhexylglycerin
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DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.