All scans / Serums / NIOD Copper Amino Isolate Serum 3 1:1
NIOD Copper Amino Isolate Serum 3 1:1 ingredients: is it worth it?
A technically elegant peptide serum, but the luxury price outruns the strength of the clinical proof.
A technically elegant peptide serum, but the luxury price outruns the strength of the clinical proof.
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The efficacy score is 3.5/5: glycerin appears near the top, the crosslinked hyaluronate supports sustained hydration, and the copper-peptide system is positioned unusually high for a peptide serum, but the formula provides no disclosed concentration for most peptides and lacks a strong anti-aging benchmark such as a retinoid. The evidence for topical copper peptides is promising but limited and mixed, so the score reflects plausible supportive benefits rather than proven transformational results.
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DemythSkin rates NIOD Copper Amino Isolate Serum 3 1:1 3.5/5 for efficacy and 4.7/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFORMULATION BASE (7)⌄
FULL INGREDIENT LIST⌄
Aqua/Water/Eau, Glycerin, Tripeptide-29, Tripeptide-1 Copper Acetate, Tripeptide-1 Acetate, Myristoyl Nonapeptide-3, Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin.
WHAT EACH INGREDIENT DOES (20)⌄
- Aqua/Water/Eau
- Solvent and formula base
- Glycerin
- Humectant for water binding
- Tripeptide-29
- Signal peptide for skin conditioning
- Tripeptide-1 Copper Acetate
- Copper peptide skin conditioning
- Tripeptide-1 Acetate
- Signal peptide skin conditioning
- Myristoyl Nonapeptide-3
- Lipidated peptide skin conditioning
- Tripeptide-2
- Signal peptide skin conditioning
- Acetyl Tetrapeptide-2
- Peptide skin conditioning
- Sodium Hyaluronate Crosspolymer
- Crosslinked humectant and film former
- Glycogen
- Humectant and skin conditioner
- Propanediol
- Solvent and humectant
- Pentylene Glycol
- Humectant and solvent
- Dimethyl Isosorbide
- Solvent and delivery enhancer
- Ethoxydiglycol
- Solvent and delivery enhancer
- Isoceteth-20
- Solubilizer and emulsifier
- Leuconostoc/Radish Root Ferment Filtrate
- Skin conditioning and preservation support
- Caprylyl Glycol
- Humectant and preservation booster
- Ethylhexylglycerin
- Preservative efficacy booster
- Phenoxyethanol
- Preservative
- Chlorphenesin
- Preservative
EXTERNAL CITATIONS
Tripeptide-1 Copper Acetate: Topical copper-peptide evidence is promising but based on limited, small, and mixed clinical studies.
Sodium Hyaluronate Crosspolymer: Crosslinked hyaluronic acid has evidence for improving hydration and reducing transepidermal water loss.
Glycerin: Glycerin is a well-established topical humectant that supports stratum-corneum hydration.
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
A cheaper serum that scores as high or higher
A different formula for the same concern (anti-aging) that scores at least as high on both efficacy and safety.
NIOD Copper Amino Isolate Serum 3 1:1: common questions
Is NIOD Copper Amino Isolate Serum 3 1:1 worth it?
NIOD Copper Amino Isolate Serum 3 1:1 scores 3.5 out of 5.0 for efficacy (Modest) and 4.7 out of 5.0 for safety (Very Gentle) on DemythSkin's independent ingredient analysis. A technically elegant peptide serum, but the luxury price outruns the strength of the clinical proof.
What are the key active ingredients in NIOD Copper Amino Isolate Serum 3 1:1?
NIOD Copper Amino Isolate Serum 3 1:1 contains no gold-standard actives. Its formula is built on supporting and base ingredients rather than clinically transformative actives.
Does NIOD Copper Amino Isolate Serum 3 1:1 contain fragrance or known irritants?
DemythSkin's analysis found no flagged irritants in NIOD Copper Amino Isolate Serum 3 1:1. It scores 4.7 out of 5.0 for safety.
How is NIOD Copper Amino Isolate Serum 3 1:1 scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
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