Naturium Retinaldehyde Cream Serum 0.10% — Efficacy 3.8/5.0, Safety 4.1/5.0 | DemythSkin
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[ DemythSkin Verdict ]
Naturium Retinaldehyde Cream Serum 0.10%
Naturium

Naturium Retinaldehyde Cream Serum 0.10%

SerumAnti-Aging
Efficacy
Solid
3.8 / 5.0
Safety
Mostly Safe
4.1 / 5.0
System Verdict
Strong retinal formula, but the supporting cast is mostly hydration and texture scaffolding rather than additional treatment power. The efficacy score is driven by retinal being a real retinoid active in a meaningful position, plus a well-built emollient/humectant base that should support tolerability; it is not boosted by the yeast/pomegranate/nucleotide marketing system because those ingredients are not the main evidence-based drivers here. The score is held below perfection because retinal efficacy depends on long-term use and irritation management, while the rest of the formula is largely supportive rather than multiplicative.
Active Ingredients Detected
S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative
Retinal
A Tier: Good BasicsProven Results
GlycerinTocopherolAdenosine Phosphate
B Tier: Supporting IngredientsPromising Ingredients
TriheptanoinC13-15 AlkaneSoy Amino AcidsDilinoleic Acid/Butanediol CopolymerCelluloseGuanosineUracilC9-12 AlkaneGlyceryl PolyacrylatePVM/MA CopolymerCastor Oil/IPDI CopolymerHexadecene
C Tier: Marketing IdolsHype | Limited or Weak Data
Faex (Yeast) ExtractPunica Granatum Seed ExtractHydrolyzed Yeast ExtractOlivine Extract
D Tier: Potential IrritantsBe Cautious
T-Butyl Alcohol
What Each Ingredient Does
Aqua (Water)
solvent base
Glycerin
humectant
Propanediol
solvent humectant
Triheptanoin
emollient
C13-15 Alkane
light emollient
Coco-Caprylate/Caprate
silky emollient
Carbomer
gel thickener
Faex (Yeast) Extract
ferment extract
Apricot Kernel Oil Polyglyceryl-6 Esters
emulsifier
Soy Amino Acids
skin conditioning
Punica Granatum Seed Extract
botanical extract
Cetyl Diglyceryl Tris (Trimethylsiloxy) Silylethyl Dimethicone
texture modifier
Hydrolyzed Yeast Extract
ferment extract
Olivine Extract
botanical extract
Dilinoleic Acid/Butanediol Copolymer
film former
Cellulose
bulking thickener
Phenoxyethanol
preservative
Sorbitan Oleate
emulsifier
Sodium Metabisulfite
antioxidant preservative
Retinal
retinoid active
Guanosine
nucleotide component
Uracil
nucleotide component
Polyacrylate Crosspolymer-6
texture polymer
C9-12 Alkane
light emollient
Full Ingredient List (INCI)

Aqua (Water), Glycerin, Propanediol, Triheptanoin, C13-15 Alkane, Coco-Caprylate/Caprate, Carbomer, Faex (Yeast) Extract, Apricot Kernel Oil Polyglyceryl-6 Esters, Soy Amino Acids, Punica Granatum Seed Extract, Cetyl Diglyceryl Tris (Trimethylsiloxy) Silylethyl Dimethicone, Hydrolyzed Yeast Extract, Olivine Extract, Dilinoleic Acid/Butanediol Copolymer, Cellulose, Phenoxyethanol, Sorbitan Oleate, Sodium Metabisulfite, Retinal, Guanosine, Uracil, Polyacrylate Crosspolymer-6, C9-12 Alkane, Caprylyl Glycol, Polyglyceryl-10 Dipalmitate, Dipropylene Glycol, Sodium Hydroxide, Glyceryl Polyacrylate, Tocopherol, PVM/MA Copolymer, Adenosine Phosphate, Castor Oil/IPDI Copolymer, Potassium Sorbate, Hexadecene, Sodium Benzoate, T-Butyl Alcohol.

Frequently Asked

Is Naturium Retinaldehyde Cream Serum 0.10% worth it?

Naturium Retinaldehyde Cream Serum 0.10% scores 3.8 out of 5.0 for efficacy (Solid) and 4.1 out of 5.0 for safety (Mostly Safe) on DemythSkin's independent ingredient analysis. Strong retinal formula, but the supporting cast is mostly hydration and texture scaffolding rather than additional treatment power. The efficacy score is driven by retinal being a real retinoid active in a meaningful pos

What are the key active ingredients in Naturium Retinaldehyde Cream Serum 0.10%?

Naturium Retinaldehyde Cream Serum 0.10% contains these gold-standard actives with strong clinical evidence: Retinal.

Does Naturium Retinaldehyde Cream Serum 0.10% contain fragrance or known irritants?

DemythSkin flags these ingredients in Naturium Retinaldehyde Cream Serum 0.10% as potential irritants: T-Butyl Alcohol.

How is Naturium Retinaldehyde Cream Serum 0.10% scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

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Analysis last updated: 2026-09-17. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score. DemythSkin earns commission from affiliate links (Amazon Associates and others). Scores are computed before any commercial relationship — the link follows the verdict, never the other way around.