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[ DemythSkin Verdict ]

Naturium

Naturium Multi-Peptide Advanced Serum

Name: Naturium Multi-Peptide Advanced Serum
Brand: Naturium

SerumAnti-Aging

Efficacy

Solid

3.8 / 5.0

Safety

Safe

4.6 / 5.0

System Verdict

This is a well-formulated peptide-focused serum that realistically offers modest anti-aging and antioxidant support rather than miracle-level results. The efficacy score is driven by a peptide cluster (acetyl hexapeptide-8, copper peptide and palmitoylated peptide complex) sitting in the mid-INCIs, combined with solid humectant and emollient support (glycerin, squalane, shea, triglycerides) and an evidence-backed antioxidant (ferulic acid) in a non-oxidative, pump-friendly format; however, absence of gold-standard actives like retinoids or high-evidence brightening agents keeps it in the “good but not powerhouse” range, and collagen here functions mainly as marketing and film-former rather than a true performance driver.

Active Ingredients Detected

A Tier: Good BasicsProven Results

SqualaneButyrospermum Parkii (Shea) ButterFerulic AcidPalmitoyl sh-Hexapeptide-13 Serine SP AmideGlycerinTocopherolDiglycerinTocopheryl Acetate

B Tier: Supporting IngredientsPromising Ingredients

IsopentyldiolEthylhexyl PolyhydroxystearateTetradecaneMannitolPhosphatidylcholineAcetyl Hexapeptide-8Copper Palmitoyl Heptapeptide-14PullulanHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerHydroxyacetophenoneSorbitan IsostearatePolyvinyl AlcoholSodium Chloride

C Tier: Marketing IdolsHype | Limited or Weak Data

Helianthus Annuus (Sunflower) ExtractOryza Sativa (Rice) Bran ExtractHydrolyzed CollagenRosmarinus Officinalis (Rosemary) Leaf Extract

What Each Ingredient Does

Aqua/Water/Eau: Solvent for ingredients
Propanediol: Solvent and penetration enhancer
Caprylic/Capric Triglyceride: Emollient and texture enhancer
Isopentyldiol: Humectant and solvent
Ethylhexyl Polyhydroxystearate: Emollient and dispersing agent
Squalane: Lightweight emollient for barrier support
Tetradecane: Emollient and spreading agent
Glyceryl Stearate Citrate: Emulsifier stabilizing oil-in-water
Butyrospermum Parkii (Shea) Butter: Rich emollient and occlusive
Polyglyceryl-3 Stearate: Emulsifier and stabilizer
Helianthus Annuus (Sunflower) Extract: Botanical extract, antioxidant support
Oryza Sativa (Rice) Bran Extract: Botanical extract, antioxidant support
Mannitol: Humectant and stabilizer
Phosphatidylcholine: Emulsifier and delivery aid
Ferulic Acid: Antioxidant protecting against free radicals
Arginine: Amino acid, pH adjuster and humectant
Acetyl Hexapeptide-8: Signal peptide for wrinkle care
Copper Palmitoyl Heptapeptide-14: Peptide complex for skin firmness
Palmitoyl sh-Hexapeptide-13 Serine SP Amide: Peptide derivative for skin renewal
Hydrolyzed Collagen: Film-forming humectant (marketing idol)
Rosmarinus Officinalis (Rosemary) Leaf Extract: Antioxidant botanical extract
Lactic Acid/Glycolic Acid Copolymer: Polymer for texture, mild exfoliation
Glycerin: Core humectant for hydration
Tocopherol: Antioxidant (vitamin E)

Full Ingredient List (INCI)

Aqua/Water/Eau, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii (Shea) Butter, Polyglyceryl-3 Stearate, Helianthus Annuus (Sunflower) Extract, Oryza Sativa (Rice) Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl sh-Hexapeptide-13 Serine SP Amide, Hydrolyzed Collagen, Rosmarinus Officinalis (Rosemary) Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol.

Frequently Asked

Is Naturium Multi-Peptide Advanced Serum worth it?

Naturium Multi-Peptide Advanced Serum scores 3.8 out of 5.0 for efficacy (Solid) and 4.6 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. This is a well-formulated peptide-focused serum that realistically offers modest anti-aging and antioxidant support rather than miracle-level results. The efficacy score is driven by a peptide cluster (acetyl hexapeptide

What are the key active ingredients in Naturium Multi-Peptide Advanced Serum?

Naturium Multi-Peptide Advanced Serum contains no gold-standard actives — its formula is built on supporting and base ingredients rather than clinically transformative actives.

Does Naturium Multi-Peptide Advanced Serum contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in Naturium Multi-Peptide Advanced Serum. It scores 4.6 out of 5.0 for safety.

How is Naturium Multi-Peptide Advanced Serum scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

Analyze on DemythSkin →

Analysis last updated: 2026-08-21. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.