All scans / Serums / Naturium Multi-Peptide Advanced Serum
Naturium Multi-Peptide Advanced Serum ingredients: is it worth it?
This is a well-formulated peptide-focused serum that realistically offers modest anti-aging and antioxidant support rather than miracle-level results.
This is a well-formulated peptide-focused serum that realistically offers modest anti-aging and antioxidant support rather than miracle-level results.
READ MORE
The efficacy score is driven by a peptide cluster (acetyl hexapeptide-8, copper peptide and palmitoylated peptide complex) sitting in the mid-INCIs, combined with solid humectant and emollient support (glycerin, squalane, shea, triglycerides) and an evidence-backed antioxidant (ferulic acid) in a non-oxidative, pump-friendly format; however, absence of gold-standard actives like retinoids or high-evidence brightening agents keeps it in the “good but not powerhouse” range, and collagen here functions mainly as marketing and film-former rather than a true performance driver.
We may earn a commission from qualifying purchases. Links never influence scores.
DemythSkin rates Naturium Multi-Peptide Advanced Serum 3.8/5 for efficacy and 4.6/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFORMULATION BASE (22)⌄
FULL INGREDIENT LIST⌄
Aqua/Water/Eau, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii (Shea) Butter, Polyglyceryl-3 Stearate, Helianthus Annuus (Sunflower) Extract, Oryza Sativa (Rice) Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl sh-Hexapeptide-13 Serine SP Amide, Hydrolyzed Collagen, Rosmarinus Officinalis (Rosemary) Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol.
WHAT EACH INGREDIENT DOES (24)⌄
- Aqua/Water/Eau
- Solvent for ingredients
- Propanediol
- Solvent and penetration enhancer
- Caprylic/Capric Triglyceride
- Emollient and texture enhancer
- Isopentyldiol
- Humectant and solvent
- Ethylhexyl Polyhydroxystearate
- Emollient and dispersing agent
- Squalane
- Lightweight emollient for barrier support
- Tetradecane
- Emollient and spreading agent
- Glyceryl Stearate Citrate
- Emulsifier stabilizing oil-in-water
- Butyrospermum Parkii (Shea) Butter
- Rich emollient and occlusive
- Polyglyceryl-3 Stearate
- Emulsifier and stabilizer
- Helianthus Annuus (Sunflower) Extract
- Botanical extract, antioxidant support
- Oryza Sativa (Rice) Bran Extract
- Botanical extract, antioxidant support
- Mannitol
- Humectant and stabilizer
- Phosphatidylcholine
- Emulsifier and delivery aid
- Ferulic Acid
- Antioxidant protecting against free radicals
- Arginine
- Amino acid, pH adjuster and humectant
- Acetyl Hexapeptide-8
- Signal peptide for wrinkle care
- Copper Palmitoyl Heptapeptide-14
- Peptide complex for skin firmness
- Palmitoyl sh-Hexapeptide-13 Serine SP Amide
- Peptide derivative for skin renewal
- Hydrolyzed Collagen
- Film-forming humectant (marketing idol)
- Rosmarinus Officinalis (Rosemary) Leaf Extract
- Antioxidant botanical extract
- Lactic Acid/Glycolic Acid Copolymer
- Polymer for texture, mild exfoliation
- Glycerin
- Core humectant for hydration
- Tocopherol
- Antioxidant (vitamin E)
EXTERNAL CITATIONS
Acetyl Hexapeptide-8: Topical acetyl hexapeptide-8 has been reported to reduce wrinkle depth via interference with neurotransmitter release at the neuromuscular junction, offering a cosmetic smoothing effect in clinical and in vitro studies.
Copper peptides: Copper peptide complexes such as glycyl-L-histidyl-L-lysine–Cu have evidence for promoting collagen synthesis and wound healing, supporting their use for anti-aging and skin repair.
Ferulic Acid: Ferulic acid is a phenolic antioxidant that can stabilize vitamins C and E and enhance protection against oxidative stress and UV-induced damage when used topically.
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
Naturium Multi-Peptide Advanced Serum: common questions
Is Naturium Multi-Peptide Advanced Serum worth it?
Naturium Multi-Peptide Advanced Serum scores 3.8 out of 5.0 for efficacy (Modest) and 4.6 out of 5.0 for safety (Very Gentle) on DemythSkin's independent ingredient analysis. This is a well-formulated peptide-focused serum that realistically offers modest anti-aging and antioxidant support rather than miracle-level results.
What are the key active ingredients in Naturium Multi-Peptide Advanced Serum?
Naturium Multi-Peptide Advanced Serum contains no gold-standard actives. Its formula is built on supporting and base ingredients rather than clinically transformative actives.
Does Naturium Multi-Peptide Advanced Serum contain fragrance or known irritants?
DemythSkin's analysis found no flagged irritants in Naturium Multi-Peptide Advanced Serum. It scores 4.6 out of 5.0 for safety.
How is Naturium Multi-Peptide Advanced Serum scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
Free scores for every product in the database, or see them on Sephora, Ulta and Amazon with the Chrome extension.