Mary & May 6 Peptide Complex Serum — Efficacy 3.2/5.0, Safety 4.7/5.0 | DemythSkin
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[ DemythSkin Verdict ]
Mary & May 6 Peptide Complex Serum
Mary&May

Mary & May 6 Peptide Complex Serum

SerumHydration
Efficacy
Basic
3.2 / 5.0
Safety
Safe
4.7 / 5.0
System Verdict
This is a minimalist hydration gel with trace-level peptides, not a heavy-hitting anti-aging serum. The base is dominated by standard humectants (glycerin, glycols, glycereth-26) and a simple gel matrix, which reliably boosts surface hydration but offers no substantial barrier lipids or brightening actives; the advertised peptides are explicitly dosed at 2 ppm (0.0002%) each, far below typical cosmetic peptide usage ranges, so they function more as marketing highlights than drivers of clinical anti-aging, while adenosine in a mid-list position adds modest evidence-backed wrinkle support without transforming the formula into a top-tier treatment.
Active Ingredients Detected
A Tier: Good BasicsProven Results
GlycerinAdenosine
B Tier: Supporting IngredientsPromising Ingredients
Glycereth-26Copper Tripeptide-1Hexapeptide-11Hexapeptide-9Palmitoyl Pentapeptide-4Palmitoyl Tripeptide-1Tripeptide-1
What Each Ingredient Does
Water
Solvent and vehicle
Glycereth-26
Humectant and skin conditioner
1,2-Hexanediol
Solvent and preservative booster
Butylene Glycol
Humectant and penetration enhancer
Glycerin
Primary humectant for hydration
Arginine
Amino acid, pH adjuster
Carbomer
Gel thickener and stabilizer
Ethylhexylglycerin
Preservative and emollient
Polyglyceryl-10 Laurate
Emulsifier and surfactant
Adenosine
Skin-conditioning and anti-wrinkle agent
Caprylyl Glycol
Humectant and preservative booster
Copper Tripeptide-1
Signal peptide for skin repair
Hexapeptide-11
Peptide for skin conditioning
Hexapeptide-9
Peptide for firming support
Palmitoyl Pentapeptide-4
Collagen-support signal peptide
Palmitoyl Tripeptide-1
Matrix-support signal peptide
Tripeptide-1
Peptide for skin repair signaling
Full Ingredient List (INCI)

Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Adenosine, Caprylyl Glycol, Copper Tripeptide-1 (2ppm), Hexapeptide-11 (2ppm), Hexapeptide-9 (2ppm), Palmitoyl Pentapeptide-4 (2ppm), Palmitoyl Tripeptide-1 (2ppm), Tripeptide-1 (2ppm) Ingredients subject to change at manufacturer&

Frequently Asked

Is Mary & May 6 Peptide Complex Serum worth it?

Mary & May 6 Peptide Complex Serum scores 3.2 out of 5.0 for efficacy (Basic) and 4.7 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. This is a minimalist hydration gel with trace-level peptides, not a heavy-hitting anti-aging serum. The base is dominated by standard humectants (glycerin, glycols, glycereth-26) and a simple gel matrix, which reliably b

What are the key active ingredients in Mary & May 6 Peptide Complex Serum?

Mary & May 6 Peptide Complex Serum contains no gold-standard actives — its formula is built on supporting and base ingredients rather than clinically transformative actives.

Does Mary & May 6 Peptide Complex Serum contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in Mary & May 6 Peptide Complex Serum. It scores 4.7 out of 5.0 for safety.

How is Mary & May 6 Peptide Complex Serum scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

Analyze on DemythSkin →

Analysis last updated: 2026-08-29. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.