All scans / Serums / Mary & May 6 Peptide Complex Serum
Mary & May 6 Peptide Complex Serum ingredients: is it worth it?
This is a minimalist hydration gel with trace-level peptides, not a heavy-hitting anti-aging serum.

This is a minimalist hydration gel with trace-level peptides, not a heavy-hitting anti-aging serum.
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The base is dominated by standard humectants (glycerin, glycols, glycereth-26) and a simple gel matrix, which reliably boosts surface hydration but offers no substantial barrier lipids or brightening actives; the advertised peptides are explicitly dosed at 2 ppm (0.0002%) each, far below typical cosmetic peptide usage ranges, so they function more as marketing highlights than drivers of clinical anti-aging, while adenosine in a mid-list position adds modest evidence-backed wrinkle support without transforming the formula into a top-tier treatment.
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DemythSkin rates Mary & May 6 Peptide Complex Serum 3.2/5 for efficacy and 4.7/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFORMULATION BASE (8)⌄
FULL INGREDIENT LIST⌄
Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Adenosine, Caprylyl Glycol, Copper Tripeptide-1 (2ppm), Hexapeptide-11 (2ppm), Hexapeptide-9 (2ppm), Palmitoyl Pentapeptide-4 (2ppm), Palmitoyl Tripeptide-1 (2ppm), Tripeptide-1 (2ppm) Ingredients subject to change at manufacturer&
WHAT EACH INGREDIENT DOES (17)⌄
- Water
- Solvent and vehicle
- Glycereth-26
- Humectant and skin conditioner
- 1,2-Hexanediol
- Solvent and preservative booster
- Butylene Glycol
- Humectant and penetration enhancer
- Glycerin
- Primary humectant for hydration
- Arginine
- Amino acid, pH adjuster
- Carbomer
- Gel thickener and stabilizer
- Ethylhexylglycerin
- Preservative and emollient
- Polyglyceryl-10 Laurate
- Emulsifier and surfactant
- Adenosine
- Skin-conditioning and anti-wrinkle agent
- Caprylyl Glycol
- Humectant and preservative booster
- Copper Tripeptide-1
- Signal peptide for skin repair
- Hexapeptide-11
- Peptide for skin conditioning
- Hexapeptide-9
- Peptide for firming support
- Palmitoyl Pentapeptide-4
- Collagen-support signal peptide
- Palmitoyl Tripeptide-1
- Matrix-support signal peptide
- Tripeptide-1
- Peptide for skin repair signaling
EXTERNAL CITATIONS
Adenosine: Adenosine-containing topical formulations have demonstrated improvements in crow's feet wrinkles and glabellar frown lines in controlled clinical studies, supporting its use as an anti-wrinkle cosmetic ingredient.
Palmitoyl Pentapeptide-4: Palmitoyl pentapeptide-based formulations have been reported to improve skin texture and reduce wrinkles in cosmetic studies, likely via upregulation of extracellular matrix components.
Copper Tripeptide-1: Copper tripeptide complexes have shown potential to enhance wound healing and stimulate dermal remodeling, suggesting supportive roles in skin repair and anti-aging when used at effective concentrations.
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
Mary & May 6 Peptide Complex Serum: common questions
Is Mary & May 6 Peptide Complex Serum worth it?
Mary & May 6 Peptide Complex Serum scores 3.2 out of 5.0 for efficacy (Mid) and 4.7 out of 5.0 for safety (Very Gentle) on DemythSkin's independent ingredient analysis. This is a minimalist hydration gel with trace-level peptides, not a heavy-hitting anti-aging serum.
What are the key active ingredients in Mary & May 6 Peptide Complex Serum?
Mary & May 6 Peptide Complex Serum contains no gold-standard actives. Its formula is built on supporting and base ingredients rather than clinically transformative actives.
Does Mary & May 6 Peptide Complex Serum contain fragrance or known irritants?
DemythSkin's analysis found no flagged irritants in Mary & May 6 Peptide Complex Serum. It scores 4.7 out of 5.0 for safety.
How is Mary & May 6 Peptide Complex Serum scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
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