Lion Pair Acne Cream W — Efficacy 3.2/5.0, Safety 4.2/5.0 | DemythSkin
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[ DemythSkin Verdict ]
Lion Pair Acne Cream W

Lion Pair Acne Cream W

SerumAcne
Efficacy
Basic
3.2 / 5.0
Safety
Mostly Safe
4.2 / 5.0
System Verdict
Effective Japanese drugstore spot treatment for mild acne inflammation and bacteria, but fragrance drags down safety. Efficacy score of 3.1 reflects clinically-backed 3% Ibuprofen Piconol (potent anti-inflammatory at high position 1) paired with 0.3% Isopropyl Methylphenol (effective antibacterial), supported by Japanese dermatology guidelines and studies showing faster lesion reduction vs single agents; no pH or stability issues in this leave-on cream format, earning outstanding rating for targeted acne action without harsh drying.
Active Ingredients Detected
B Tier: Supporting IngredientsPromising Ingredients
Ibuprofen PiconolIsopropyl MethylphenolDisodium EdetateOctyldodecanolCarboxyvinyl Polymer
D Tier: Potential IrritantsBe Cautious
ParabensDiisopropanolamineFragrance
What Each Ingredient Does
Ibuprofen Piconol
Anti-inflammatory agent
Isopropyl Methylphenol
Antibacterial preservative
Stearyl Alcohol
Emollient viscosity controller
Polysorbate 60
Emulsifying surfactant
Disodium Edetate
Chelating agent
Parabens
Preservative
Diisopropanolamine
pH adjuster
Octyldodecanol
Emollient perfuming agent
1,3 Butylene Glycol
Humectant solvent
Carboxyvinyl Polymer
Viscosity controlling thickener
Fragrance
Perfuming agent
Full Ingredient List (INCI)

Ibuprofen Piconol (3%), Isopropyl Methylphenol (0.3%), Stearyl Alcohol, Polysorbate 60, Disodium Edetate, Parabens, Diisopropanolamine, Octyldodecanol, 1,3 Butylene Glycol, Carboxyvinyl Polymer, Fragrance

Frequently Asked

Is Lion Pair Acne Cream W worth it?

Lion Pair Acne Cream W scores 3.2 out of 5.0 for efficacy (Basic) and 4.2 out of 5.0 for safety (Mostly Safe) on DemythSkin's independent ingredient analysis. Effective Japanese drugstore spot treatment for mild acne inflammation and bacteria, but fragrance drags down safety. Efficacy score of 3.1 reflects clinically-backed 3% Ibuprofen Piconol (potent anti-inflammatory at hig

What are the key active ingredients in Lion Pair Acne Cream W?

Lion Pair Acne Cream W contains no gold-standard actives — its formula is built on supporting and base ingredients rather than clinically transformative actives.

Does Lion Pair Acne Cream W contain fragrance or known irritants?

DemythSkin flags these ingredients in Lion Pair Acne Cream W as potential irritants: Parabens, Diisopropanolamine, Fragrance. This product does contain fragrance.

How is Lion Pair Acne Cream W scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

Analyze on DemythSkin →

Analysis last updated: 2026-05-09. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.