La Roche-Posay Mela B3 Niacinamide Serum
- Eau
- Primary solvent (water)
- Dimethicone
- Silicone emollient and skin protectant
- Niacinamide
- Multi-functional brightening and barrier active
- Glycerin
- Humectant for hydration
- Propylene Glycol
- Humectant and penetration enhancer
- Polysilicone-11
- Film-forming silicone, texture enhancer
- Silica
- Texture modifier and mattifying agent
- Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone
- Emulsifying silicone and texture enhancer
- Cystoseira Tamariscifolia Extract
- Botanical extract, marketed brightening support
- 2-Mercaptonicotinoyl Glycine
- Patented anti-pigmentation active
- Peg-20 Methyl Glucose Sesquistearate
- Non-ionic emulsifier
- Sodium Hyaluronate
- Hyaluronic acid salt humectant
- Sodium Hydroxide
- pH adjuster
- Sodium Thiosulfate
- Antioxidant and stabilizer
- Carnosine
- Antioxidant and anti-glycation peptide
- Poloxamer 338
- Surfactant/emulsifier and solubilizer
- Ammonium Polyacryloyldimethyl Taurate
- Polymer thickener and stabilizer
- Dipotassium Glycyrrhizate
- Licorice-derived soothing and brightening agent
- Caprylic/Capric Triglyceride
- Emollient and texture enhancer
- Capryloyl Salicylic Acid
- Gentle exfoliating and anti-spot acid
- Caprylyl Glycol
- Humectant and preservative booster
- Citric Acid
- pH adjuster and mild exfoliant
- Trisodium Ethylenediamine Disuccinate
- Chelating agent for stability
- Xanthan Gum
- Natural thickener and stabilizer
Eau, Dimethicone, Niacinamide, Glycerin, Propylene Glycol, Polysilicone-11, Silica, Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Cystoseira Tamariscifolia Extract, 2-Mercaptonicotinoyl Glycine, Peg-20 Methyl Glucose Sesquistearate, Sodium Hyaluronate, Sodium Hydroxide, Sodium Thiosulfate, Carnosine, Poloxamer 338, Ammonium Polyacryloyldimethyl Taurate, Dipotassium Glycyrrhizate, Caprylic/Capric Triglyceride, Capryloyl Salicylic Acid, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Pentylene Glycol, Octyldodecanol, Retinyl Palmitate, Tocopherol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Phenoxyethanol, Ci 17200 / Red 33, Parfum / Fragrance
Is La Roche-Posay Mela B3 Niacinamide Serum worth it?
La Roche-Posay Mela B3 Niacinamide Serum scores 4.0 out of 5.0 for efficacy (Strong) and 4.3 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. This is a well-designed, niacinamide-centered dark-spot serum with genuinely solid but not quite clinic-grade brightening power. The efficacy score is driven by high-position niacinamide as the core evidence-backed brigh
What are the key active ingredients in La Roche-Posay Mela B3 Niacinamide Serum?
La Roche-Posay Mela B3 Niacinamide Serum contains no gold-standard actives — its formula is built on supporting and base ingredients rather than clinically transformative actives.
Does La Roche-Posay Mela B3 Niacinamide Serum contain fragrance or known irritants?
DemythSkin flags these ingredients in La Roche-Posay Mela B3 Niacinamide Serum as potential irritants: Parfum / Fragrance. This product does contain fragrance.
How is La Roche-Posay Mela B3 Niacinamide Serum scored?
DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.
Analysis last updated: 2026-09-09. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.