ISOI Moisture Dr. Ampoule — Efficacy 4.2/5.0, Safety 3.9/5.0 | DemythSkin
++++
[ DemythSkin Verdict ]
ISOI Moisture Dr. Ampoule

ISOI Moisture Dr. Ampoule

SerumHydration
Efficacy
Strong
4.2 / 5.0
Safety
Mostly Safe
3.9 / 5.0
System Verdict
Strong hydrating ampoule, but the fragrance load and botanical noise keep it from elite status. The formula earns a solid efficacy score because glycerin, betaine, trehalose, multiple hyaluronic acid forms, squalane, panthenol, ceramide NP, and phytosphingosine are all placed high enough to meaningfully support hydration and barrier repair, which is exactly what this serum is built to do. It loses points because grapefruit peel oil and limonene add irritation risk, and the many plant extracts dilute the formula focus without clearly outperforming a simpler, more barrier-centric S Tier or A Tier serum; the pH is not disclosed, so there is no reason to assume optimal acid-performance conditions here.
Active Ingredients Detected
A Tier: Good BasicsProven Results
WaterGlycerinBetaineTrehaloseSqualaneCaprylic/Capric TriglyceridePanthenolSodium HyaluronateHydrolyzed Hyaluronic AcidHyaluronic AcidSodium Hyaluronate CrosspolymerHouttuynia Cordata ExtractLactobacillus/Soybean Ferment ExtractArginineMacadamia Ternifolia Seed OilPhytosphingosineCeramide NPHydrogenated Lecithin
B Tier: Supporting IngredientsPromising Ingredients
Hydrolyzed GlycosaminoglycansCarbomerXanthan GumSorbitan SesquioleateButylene Glycol1,2-HexanediolPropanediol
C Tier: Marketing IdolsHype | Limited or Weak Data
Melaleuca Alternifolia (Tea Tree) Leaf ExtractPortulaca Oleracea ExtractSalix Alba (Willow) Bark ExtractOriganum Vulgare Leaf ExtractChamaecyparis Obtusa Leaf ExtractCinnamomum Cassia Bark ExtractCalendula Officinalis Flower ExtractScutellaria Baicalensis Root ExtractPaeonia Suffruticosa Root ExtractGlycyrrhiza Glabra (Licorice) Root Extract
D Tier: Potential IrritantsBe Cautious
Citrus Paradisi (Grapefruit) Peel OilLimonene
Analyze on DemythSkin

DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.