All scans / Moisturizers / DRMTLGY Peptide Night Cream
DRMTLGY Peptide Night Cream ingredients: is it worth it?
A competent barrier moisturizer with an overpriced peptide story—not a transformative anti-aging treatment.
A competent barrier moisturizer with an overpriced peptide story—not a transformative anti-aging treatment.
READ MORE
The efficacy score is 4.1/5: the formula earns credit for a substantial emollient base, glycerin, three ceramides, cholesterol, phytosphingosine, and allantoin, which directly support moisturization and barrier function. The peptide blend may offer modest cosmetic benefits, but peptide concentrations are undisclosed and most appear after the primary base ingredients, so the formula cannot justify a top-tier treatment score. Isopropyl Palmitate is also prominent enough to merit caution for acne-prone users. There is no retinoid, vitamin C, niacinamide, exfoliating acid, or other high-evidence anti-aging treatment active. The safety score is 4.2/5 because the product is fragrance-free and contains no denatured alcohol or essential oils, but prominent Isopropyl Palmitate may be problematic for comedone-prone skin.
We may earn a commission from qualifying purchases. Links never influence scores.
DemythSkin rates DRMTLGY Peptide Night Cream 4.1/5 for efficacy and 4.2/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFORMULATION BASE (18)⌄
FULL INGREDIENT LIST⌄
Water/Aqua/Eau, Dimethicone, Propanediol, Glyceryl Stearate, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Isopropyl Palmitate, Glycerin, Undecane Butyrospermum Parkii (Shea) Butter, Cetyl Alcohol, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Dydroxythreonine, Palmitoyl Tripeptide-5, Tripeptide-2, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Tridecane, Ceramide NP, Ceramide AP, Phytosphingosine, Cholesterol, Phenoxyethanol, Glycol Distearate, Butylene Glycol, Tocopherol, Potassium Cetyl Phosphate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Ethylhexylglycerin, Disodium EDTA, Sodium Lauroyl Lactylate, Sodium Hydroxide, Carbomer, Polysorbate 20, Xanthan Gum, Tetradecyl Aminobutyroylvalylaminobutyric Urea Acetate, Magnesium Chloride
WHAT EACH INGREDIENT DOES (24)⌄
- Water/Aqua/Eau
- solvent and formula base
- Dimethicone
- silicone emollient and occlusive
- Propanediol
- humectant and solvent
- Glyceryl Stearate
- emollient and emulsifier
- C12-15 Alkyl Benzoate
- lightweight emollient
- Caprylic/Capric Triglyceride
- emollient skin conditioner
- Isopropyl Palmitate
- emollient texture enhancer
- Glycerin
- humectant moisture binder
- Undecane Butyrospermum Parkii (Shea) Butter
- emollient and occlusive
- Cetyl Alcohol
- fatty alcohol and thickener
- PEG-100 Stearate
- emulsifier and stabilizer
- Palmitoyl Dipeptide-5 Diaminobutyroyl Dydroxythreonine
- signal peptide complex
- Palmitoyl Tripeptide-5
- signal peptide
- Tripeptide-2
- synthetic signaling peptide
- Palmitoyl Tripeptide-1
- signal peptide
- Palmitoyl Tetrapeptide-7
- signal peptide
- Ceramide EOP
- barrier lipid
- Tridecane
- texture-enhancing emollient
- Ceramide NP
- barrier lipid
- Ceramide AP
- barrier lipid
- Phytosphingosine
- barrier lipid precursor
- Cholesterol
- barrier lipid component
- Phenoxyethanol
- preservative
- Glycol Distearate
- opacifier and texture agent
EXTERNAL CITATIONS
Ceramides NP, AP, and EOP: The official product page describes a three-ceramide complex intended to support the skin barrier.
Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, and Palmitoyl Tetrapeptide-7: The official product page identifies these as peptide ingredients associated with firmness and wrinkle-focused positioning.
Glycerin: Glycerin is a well-established humectant used to increase water content in the outer skin layer.
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
A cheaper moisturizer that scores as high or higher
A different formula for the same concern (barrier repair) that scores at least as high on both efficacy and safety.
DRMTLGY Peptide Night Cream: common questions
Is DRMTLGY Peptide Night Cream worth it?
DRMTLGY Peptide Night Cream scores 4.1 out of 5.0 for efficacy (Effective) and 4.2 out of 5.0 for safety (Gentle) on DemythSkin's independent ingredient analysis. A competent barrier moisturizer with an overpriced peptide story—not a transformative anti-aging treatment.
What are the key active ingredients in DRMTLGY Peptide Night Cream?
DRMTLGY Peptide Night Cream contains no gold-standard actives. Its formula is built on supporting and base ingredients rather than clinically transformative actives.
Does DRMTLGY Peptide Night Cream contain fragrance or known irritants?
DemythSkin's analysis found no flagged irritants in DRMTLGY Peptide Night Cream. It scores 4.2 out of 5.0 for safety.
How is DRMTLGY Peptide Night Cream scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
Free scores for every product in the database, or see them on Sephora, Ulta and Amazon with the Chrome extension.