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Clinique Dramatically Different Moisturizing Lotion+ ingredients: is it worth it?
Competent, old-school barrier moisturizer — not a treatment cream, just a solid hydrator.

Competent, old-school barrier moisturizer — not a treatment cream, just a solid hydrator.
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The efficacy score is driven by a strong humectant-and-occlusive base (glycerin, urea, sodium hyaluronate, mineral oil, petrolatum) plus supportive emollients, which should meaningfully reduce water loss and improve softness. It loses points because the formula is largely basic moisturization rather than a high-potency repair treatment, and the botanical extracts are supporting players rather than primary drivers of benefit.
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DemythSkin rates Clinique Dramatically Different Moisturizing Lotion+ 4.0/5 for efficacy and 4.4/5 for safety.
ACTIVE INGREDIENTS BY TIER
Gold Standards
High clinical proof | Skin-transformativeReliable
Proven resultsPotent
Developing evidenceOverhyped | Marketing
Hype | Limited dataDocumented Irritants
Evidence-backed flagFORMULATION BASE (11)⌄
FULL INGREDIENT LIST⌄
Water, Mineral Oil/Paraffinum Liquidum/Huile Minerale, Glycerin, Petrolatum, Stearic Acid, Glyceryl Stearate, Sesamum Indicum (Sesame) Oil, Urea, Lanolin Alcohol, Triethanolamine, Hordeum Vulgare (Barley) Extract, Cucumis Sativus (Cucumber) Fruit Extract, Helianthus Annuus (Sunflower) Seedcake, Propylene Glycol Dicaprate, Sodium Hyaluronate, Butylene Glycol, Pentylene Glycol, Trisodium EDTA, Phenoxyethanol, Yellow 6 (CI 15985), Yellow 5 (CI 19140), Red 33 (CI 17200).
WHAT EACH INGREDIENT DOES (22)⌄
- Water
- solvent base
- Mineral Oil/Paraffinum Liquidum/Huile Minerale
- occlusive emollient
- Glycerin
- humectant hydration
- Petrolatum
- strong occlusive sealant
- Stearic Acid
- fatty acid thickener
- Glyceryl Stearate
- emollient emulsifier
- Sesamum Indicum (Sesame) Oil
- emollient oil
- Urea
- humectant support
- Lanolin Alcohol
- emollient emulsifier
- Triethanolamine
- pH adjuster
- Hordeum Vulgare (Barley) Extract
- botanical soothing
- Cucumis Sativus (Cucumber) Fruit Extract
- botanical soothing
- Helianthus Annuus (Sunflower) Seedcake
- botanical support
- Propylene Glycol Dicaprate
- light emollient
- Sodium Hyaluronate
- water-binding humectant
- Butylene Glycol
- solvent humectant
- Pentylene Glycol
- humectant preservative aid
- Trisodium EDTA
- chelating agent
- Phenoxyethanol
- preservative
- Yellow 6 (CI 15985)
- colorant
- Yellow 5 (CI 19140)
- colorant
- Red 33 (CI 17200)
- colorant
EXTERNAL CITATIONS
Glycerin: Clinique identifies pure glycerin as a key humectant that supports the skin barrier by attracting and retaining moisture.
Urea: Clinique identifies pure urea as a humectant that helps pull in water and bind moisture to skin.
Sodium Hyaluronate: Sephora and Clinique list sodium hyaluronate in the formula and describe hyaluronic acid as a moisture-binding hydrator.
Petrolatum: The formula includes petrolatum, a classic occlusive that helps reduce transepidermal water loss.
DISCLAIMER: THIS ANALYSIS IS FOR INFORMATION ONLY. NOT MEDICAL ADVICE. AI-GENERATED DATA BASED ON PUBLICLY AVAILABLE INGREDIENT LISTS. VERIFY WITH A MEDICAL PROFESSIONAL.
Clinique Dramatically Different Moisturizing Lotion+: common questions
Is Clinique Dramatically Different Moisturizing Lotion+ worth it?
Clinique Dramatically Different Moisturizing Lotion+ scores 4.0 out of 5.0 for efficacy (Effective) and 4.4 out of 5.0 for safety (Gentle) on DemythSkin's independent ingredient analysis. Competent, old-school barrier moisturizer — not a treatment cream, just a solid hydrator.
What are the key active ingredients in Clinique Dramatically Different Moisturizing Lotion+?
Clinique Dramatically Different Moisturizing Lotion+ contains no gold-standard actives. Its formula is built on supporting and base ingredients rather than clinically transformative actives.
Does Clinique Dramatically Different Moisturizing Lotion+ contain fragrance or known irritants?
DemythSkin flags these ingredients in Clinique Dramatically Different Moisturizing Lotion+ as documented irritants: Lanolin Alcohol.
How is Clinique Dramatically Different Moisturizing Lotion+ scored?
DemythSkin grades every product on two independent scores: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are graded S through D against a database of over 3,000 compounds. Brand and price are not part of the score, and no brand pays for one.
Free scores for every product in the database, or see them on Sephora, Ulta and Amazon with the Chrome extension.