Clinique Dramatically Different Moisturizing Lotion+ — Efficacy 3.7/5.0, Safety 4.4/5.0 | DemythSkin
++++
[ DemythSkin Verdict ]
Clinique Dramatically Different Moisturizing Lotion+
CLINIQUE

Clinique Dramatically Different Moisturizing Lotion+

MoisturizerBarrier Repair
Efficacy
Basic
3.7 / 5.0
Safety
Safe
4.4 / 5.0
System Verdict
Competent, old-school barrier moisturizer — not a treatment cream, just a solid hydrator. The efficacy score is driven by a strong humectant-and-occlusive base (glycerin, urea, sodium hyaluronate, mineral oil, petrolatum) plus supportive emollients, which should meaningfully reduce water loss and improve softness. It loses points because the formula is largely basic moisturization rather than a high-potency repair treatment, and the botanical extracts are supporting players rather than primary drivers of benefit.
Active Ingredients Detected
A Tier: Good BasicsProven Results
GlycerinPetrolatumUreaSodium Hyaluronate
B Tier: Supporting IngredientsPromising Ingredients
Mineral Oil/Paraffinum Liquidum/Huile MineraleSesamum Indicum (Sesame) OilHelianthus Annuus (Sunflower) SeedcakeRed 33 (CI 17200)
C Tier: Marketing IdolsHype | Limited or Weak Data
Hordeum Vulgare (Barley) ExtractCucumis Sativus (Cucumber) Fruit Extract
D Tier: Potential IrritantsBe Cautious
Lanolin Alcohol
What Each Ingredient Does
Water
solvent base
Mineral Oil/Paraffinum Liquidum/Huile Minerale
occlusive emollient
Glycerin
humectant hydration
Petrolatum
strong occlusive sealant
Stearic Acid
fatty acid thickener
Glyceryl Stearate
emollient emulsifier
Sesamum Indicum (Sesame) Oil
emollient oil
Urea
humectant support
Lanolin Alcohol
emollient emulsifier
Triethanolamine
pH adjuster
Hordeum Vulgare (Barley) Extract
botanical soothing
Cucumis Sativus (Cucumber) Fruit Extract
botanical soothing
Helianthus Annuus (Sunflower) Seedcake
botanical support
Propylene Glycol Dicaprate
light emollient
Sodium Hyaluronate
water-binding humectant
Butylene Glycol
solvent humectant
Pentylene Glycol
humectant preservative aid
Trisodium EDTA
chelating agent
Phenoxyethanol
preservative
Yellow 6 (CI 15985)
colorant
Yellow 5 (CI 19140)
colorant
Red 33 (CI 17200)
colorant
Full Ingredient List (INCI)

Water, Mineral Oil/Paraffinum Liquidum/Huile Minerale, Glycerin, Petrolatum, Stearic Acid, Glyceryl Stearate, Sesamum Indicum (Sesame) Oil, Urea, Lanolin Alcohol, Triethanolamine, Hordeum Vulgare (Barley) Extract, Cucumis Sativus (Cucumber) Fruit Extract, Helianthus Annuus (Sunflower) Seedcake, Propylene Glycol Dicaprate, Sodium Hyaluronate, Butylene Glycol, Pentylene Glycol, Trisodium EDTA, Phenoxyethanol, Yellow 6 (CI 15985), Yellow 5 (CI 19140), Red 33 (CI 17200).

Frequently Asked

Is Clinique Dramatically Different Moisturizing Lotion+ worth it?

Clinique Dramatically Different Moisturizing Lotion+ scores 3.7 out of 5.0 for efficacy (Basic) and 4.4 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. Competent, old-school barrier moisturizer — not a treatment cream, just a solid hydrator. The efficacy score is driven by a strong humectant-and-occlusive base (glycerin, urea, sodium hyaluronate, mineral oil, petrolatum

What are the key active ingredients in Clinique Dramatically Different Moisturizing Lotion+?

Clinique Dramatically Different Moisturizing Lotion+ contains no gold-standard actives — its formula is built on supporting and base ingredients rather than clinically transformative actives.

Does Clinique Dramatically Different Moisturizing Lotion+ contain fragrance or known irritants?

DemythSkin flags these ingredients in Clinique Dramatically Different Moisturizing Lotion+ as potential irritants: Lanolin Alcohol.

How is Clinique Dramatically Different Moisturizing Lotion+ scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

Buy on Amazon Analyze on DemythSkin

Analysis last updated: 2026-09-12. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score. DemythSkin earns commission from affiliate links (Amazon Associates and others). Scores are computed before any commercial relationship — the link follows the verdict, never the other way around.