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[ DemythSkin Verdict ]

Avène Cleanance Acne Medicated Clearing Gel Cleanser
CleanserAcne / Oil Control
Efficacy
Strong
4.2 / 5.0
Safety
Excellent
4.8 / 5.0
System Verdict
This is a clinically competent salicylic acid acne cleanser with a surprisingly gentle surfactant base—but it’s still a medicated treatment, not a fluffy sensitive-skin wash. Efficacy-wise, it earns its score because 2% salicylic acid (S Tier for acne) is at the legally required treatment level in a cleanser format and paired with an appropriate pH-buffering system, so you will get meaningful comedolytic and anti-inflammatory benefit on contact, even though it is rinse-off. The base uses milder surfactants like sodium cocoyl isethionate, coco-glucoside and cocamidopropyl hydroxysultaine (A/B Tier for barrier-friendliness) instead of harsh SLS, with humectants such as glycerin, betaine and saccharide isomerate to reduce stripping. I am not pushing the score higher because this is still an acid cleanser: you must keep it on the skin briefly to get effect, and any postbiotic/probiotic marketing (lactobacillus ferment lysate, C/D Tier in rinse-off) is essentially cosmetic in this context.
Active Ingredients Detected
S Tier: Gold StandardsHigh Clinical Proof | Skin-Transformative
Salicylic Acid
A Tier: Good BasicsProven Results
Water (Aqua)BetaineGlycerinLactobacillus Ferment Lysate
B Tier: Supporting IngredientsPromising Ingredients
Sodium Cocoyl IsethionateCocamidopropyl HydroxysultainePropanediolStearyl AlcoholCoco-GlucosideSodium Lauroyl SarcosinateGlyceryl LaurateSodium ChlorideCetearyl OlivateHydroxypropyl MethylcelluloseSodium BenzoateSaccharide IsomerateSorbitan OlivateHydroxypropyl Guar Hydroxypropyltrimonium ChlorideXanthan GumTrisodium Ethylenediamine DisuccinatePotassium SorbateCitric AcidSodium CitrateAcrylates Copolymer
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DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.