Anua PDRN Hyaluronic Acid 100 Moisturizing Cream — Efficacy 4.3/5.0, Safety 4.7/5.0 | DemythSkin
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[ DemythSkin Verdict ]
Anua PDRN Hyaluronic Acid 100 Moisturizing Cream
Anua

Anua PDRN Hyaluronic Acid 100 Moisturizing Cream

MoisturizerHydration
Efficacy
Strong
4.3 / 5.0
Safety
Safe
4.7 / 5.0
System Verdict
Hydrating workhorse with heavy marketing fluff, not a miracle repair cream. The efficacy here comes from a solid humectant base (glycerin, multiple glycols) plus a genuinely complex multi-weight hyaluronic acid system and centella-derived soothing actives, while the hyped PDRN (sodium DNA) and collagen mainly serve marketing with limited topical evidence; niacinamide is present but not high on the list, so brightening and barrier benefits are mild rather than transformative.
Active Ingredients Detected
A Tier: Good BasicsProven Results
SqualaneGlycerinNiacinamideDiglycerinAloe Barbadensis Flower ExtractSodium HyaluronateDimethylsilanol HyaluronateHydrolyzed Hyaluronic AcidHydrolyzed Sodium HyaluronatePotassium HyaluronateHyaluronic AcidHydroxypropyltrimonium HyaluronateSodium Hyaluronate CrosspolymerSodium Hyaluronate DimethylsilanolSodium Acetylated HyaluronateAdenosineMadecassosideAsiaticoside
B Tier: Supporting IngredientsPromising Ingredients
PVM/MA CopolymerC14-22 AlcoholsC12-20 Alkyl GlucosideHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerC12-13 Alketh-9Centella Asiatica Leaf Extract
C Tier: Marketing IdolsHype | Limited or Weak Data
Hydrolyzed CollagenSodium DNAMelia Azadirachta Leaf ExtractMelia Azadirachta Flower ExtractCoccinia Indica Fruit ExtractSolanum Melongena (Eggplant) Fruit ExtractOcimum Sanctum Leaf ExtractCorallina Officinalis ExtractCurcuma Longa (Turmeric) Root Extract
What Each Ingredient Does
Water
Solvent and base
Squalane
Emollient and skin conditioner
Glycerin
Primary humectant
Hydrolyzed Collagen
Film-forming humectant
1,2-Hexanediol
Solvent and preservative booster
Methylpropanediol
Solvent and penetration enhancer
Ethylhexylglycerin
Preservative booster and humectant
Niacinamide
Multifunctional brightening active
Butylene Glycol
Humectant and solvent
Sodium DNA
Marketing PDRN nucleotide ingredient
Pentylene Glycol
Humectant and solvent
PVM/MA Copolymer
Film-former and texture agent
Carbomer
Gel thickener
Diphenylsiloxy Phenyl Trimethicone
Silicone emollient
PCA Dimethicone
Silicone-based skin conditioner
Behenyl Alcohol
Fatty alcohol emollient and thickener
Ammonium Acryloyldimethyltaurate/VP Copolymer
Polymer thickener and stabilizer
Propanediol
Solvent and humectant
C14-22 Alcohols
Fatty alcohols; structure and emollient
C12-20 Alkyl Glucoside
Emulsifier and surfactant
Diglycerin
Secondary humectant
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Polymer thickener and stabilizer
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Gel thickener and stabilizer
C12-13 Alketh-9
Nonionic surfactant/emulsifier
Full Ingredient List (INCI)

Water, Squalane, Glycerin, Hydrolyzed Collagen, 1,2-Hexanediol, Methylpropanediol, Ethylhexylglycerin, Niacinamide, Butylene Glycol, Sodium DNA, Pentylene Glycol, PVM/MA Copolymer, Carbomer, Diphenylsiloxy Phenyl Trimethicone, PCA Dimethicone, Behenyl Alcohol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Propanediol, C14-22 Alcohols, C12-20 Alkyl Glucoside, Diglycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12-13 Alketh-9, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Solanum Melongena (Eggplant) Fruit Extract, Aloe Barbadensis Flower Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Curcuma Longa (Turmeric) Root Extract, Sodium Hyaluronate, Dimethylsilanol Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate, Adenosine, Sodium Phytate, Aminomethyl Propanediol, Madecassoside, Asiaticoside, Centella Asiatica Leaf Extract

Frequently Asked

Is Anua PDRN Hyaluronic Acid 100 Moisturizing Cream worth it?

Anua PDRN Hyaluronic Acid 100 Moisturizing Cream scores 4.3 out of 5.0 for efficacy (Strong) and 4.7 out of 5.0 for safety (Safe) on DemythSkin's independent ingredient analysis. Hydrating workhorse with heavy marketing fluff, not a miracle repair cream. The efficacy here comes from a solid humectant base (glycerin, multiple glycols) plus a genuinely complex multi-weight hyaluronic acid system an

What are the key active ingredients in Anua PDRN Hyaluronic Acid 100 Moisturizing Cream?

Anua PDRN Hyaluronic Acid 100 Moisturizing Cream contains no gold-standard actives — its formula is built on supporting and base ingredients rather than clinically transformative actives.

Does Anua PDRN Hyaluronic Acid 100 Moisturizing Cream contain fragrance or known irritants?

DemythSkin's analysis found no flagged irritants in Anua PDRN Hyaluronic Acid 100 Moisturizing Cream. It scores 4.7 out of 5.0 for safety.

How is Anua PDRN Hyaluronic Acid 100 Moisturizing Cream scored?

DemythSkin grades every product on two independent axes: efficacy (whether the ingredients have clinical evidence of working) and safety (irritation and sensitisation risk). Ingredients are classified S through D against a database of over 3,000 compounds. No brand pays for a score.

Analyze on DemythSkin

Analysis last updated: 2026-07-27. DemythSkin is an independent ingredient analyzer. Scores are computed by a deterministic rubric from published clinical evidence — no brand pays for a score.